PEEP Role in ICU and Operating Room: From Pathophysiology to Clinical Practice

Positive end expiratory pressure (PEEP) may prevent cyclic opening and collapsing alveoli in acute respiratory distress syndrome (ARDS) patients, but it may play a role also in general anesthesia. This review is organized in two sections. The first one reports the pathophysiological effect of PEEP o...

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Main Authors: M. Vargas, Y. Sutherasan, C. Gregoretti, P. Pelosi
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2014/852356
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author M. Vargas
Y. Sutherasan
C. Gregoretti
P. Pelosi
author_facet M. Vargas
Y. Sutherasan
C. Gregoretti
P. Pelosi
author_sort M. Vargas
collection DOAJ
description Positive end expiratory pressure (PEEP) may prevent cyclic opening and collapsing alveoli in acute respiratory distress syndrome (ARDS) patients, but it may play a role also in general anesthesia. This review is organized in two sections. The first one reports the pathophysiological effect of PEEP on thoracic pressure and hemodynamic and cerebral perfusion pressure. The second section summarizes the knowledge and evidence of the use of PEEP in general anesthesia and intensive care. More specifically, for intensive care this review refers to ARDS and traumatic brain injured patients.
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series The Scientific World Journal
spelling doaj-art-1c83d919a9a34e52bae64523a223eca02025-08-20T03:54:37ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/852356852356PEEP Role in ICU and Operating Room: From Pathophysiology to Clinical PracticeM. Vargas0Y. Sutherasan1C. Gregoretti2P. Pelosi3Department of Neurosciences and Reproductive and Odontostomatological Sciences, University of Naples “Federico II,” 80100 Naples, ItalyRamathibodi Hospital, Mahidol University, Bangkok 10400, ThailandDepartment of Critical Care Medicine, “Città della Salute e della Scienza” Hospital, 10121 Turin, ItalyDepartment of Surgical Sciences and Integrated Diagnostics, University of Genoa, 16132 Genoa, ItalyPositive end expiratory pressure (PEEP) may prevent cyclic opening and collapsing alveoli in acute respiratory distress syndrome (ARDS) patients, but it may play a role also in general anesthesia. This review is organized in two sections. The first one reports the pathophysiological effect of PEEP on thoracic pressure and hemodynamic and cerebral perfusion pressure. The second section summarizes the knowledge and evidence of the use of PEEP in general anesthesia and intensive care. More specifically, for intensive care this review refers to ARDS and traumatic brain injured patients.http://dx.doi.org/10.1155/2014/852356
spellingShingle M. Vargas
Y. Sutherasan
C. Gregoretti
P. Pelosi
PEEP Role in ICU and Operating Room: From Pathophysiology to Clinical Practice
The Scientific World Journal
title PEEP Role in ICU and Operating Room: From Pathophysiology to Clinical Practice
title_full PEEP Role in ICU and Operating Room: From Pathophysiology to Clinical Practice
title_fullStr PEEP Role in ICU and Operating Room: From Pathophysiology to Clinical Practice
title_full_unstemmed PEEP Role in ICU and Operating Room: From Pathophysiology to Clinical Practice
title_short PEEP Role in ICU and Operating Room: From Pathophysiology to Clinical Practice
title_sort peep role in icu and operating room from pathophysiology to clinical practice
url http://dx.doi.org/10.1155/2014/852356
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AT ysutherasan peeproleinicuandoperatingroomfrompathophysiologytoclinicalpractice
AT cgregoretti peeproleinicuandoperatingroomfrompathophysiologytoclinicalpractice
AT ppelosi peeproleinicuandoperatingroomfrompathophysiologytoclinicalpractice