STAT3 signaling enhances tissue expansion during postimplantation mouse development

Summary: Signal transducer and activator of transcription (STAT)3 signaling has been studied extensively using mouse embryonic stem cells. Zygotic deletion of Stat3 enables embryo implantation, but thereafter, mutants resemble non-affected littermates from the previous day until around mid-gestation...

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Bibliographic Details
Main Authors: Takuya Azami, Bart Theeuwes, Mai-Linh Nu Ton, William Mansfield, Luke Harland, Masaki Kinoshita, Berthold Gottgens, Jennifer Nichols
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725002773
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