A genomic survey of positive selection in Burkholderia pseudomallei provides insights into the evolution of accidental virulence.

A genomic survey of positive selection in Burkholderia pseudomallei provides insights into the evolution of accidental virulence.

Certain environmental microorganisms can cause severe human infections, even in the absence of an obvious requirement for transition through an animal host for replication ("accidental virulence"). To understand this process, we compared eleven isolate genomes of Burkholderia pseudomallei...

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Main Authors: Tannistha Nandi, Catherine Ong, Arvind Pratap Singh, Justin Boddey, Timothy Atkins, Mitali Sarkar-Tyson, Angela E Essex-Lopresti, Hui Hoon Chua, Talima Pearson, Jason F Kreisberg, Christina Nilsson, Pramila Ariyaratne, Catherine Ronning, Liliana Losada, Yijun Ruan, Wing-Kin Sung, Donald Woods, Richard W Titball, Ifor Beacham, Ian Peak, Paul Keim, William C Nierman, Patrick Tan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000845&type=printable
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