MicroRNA-15a-5p mediates abdominal aortic aneurysm progression and serves as a potential diagnostic and prognostic circulating biomarker

MicroRNA-15a-5p mediates abdominal aortic aneurysm progression and serves as a potential diagnostic and prognostic circulating biomarker

Abstract Background MicroRNAs are post transcriptional modulators of gene expression. We explored the diagnostic and prognostic value of circulating microRNAs in abdominal aortic aneurysm (AAA) disease, for which currently no established circulating biomarker is available. Methods We profiled the ex...

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Main Authors: Greg Winski, Ekaterina Chernogubova, Albert Busch, Suzanne M. Eken, Hong Jin, Moritz Lindquist Liljeqvist, Tooba Khan, Alexandra Bäcklund, Valentina Paloschi, Joy Roy, Rebecka Hultgren, Christine Brostjan, Gert J. de Borst, Joost P. G. Sluijter, Nadja Sachs, Hans-Henning Eckstein, Reinier A. Boon, Joshua M. Spin, Philip S. Tsao, Folkert W. Asselbergs, Lars Maegdefessel
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-00892-w
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