Is maternal SARS-CoV-2 infection in the first trimester associated with congenital heart defects?

Is maternal SARS-CoV-2 infection in the first trimester associated with congenital heart defects?

Emerging evidence suggests a potential link between maternal SARS-CoV-2 infection during early pregnancy and the development of congenital heart defects (CHD) in offspring. Although vertical transmission of SARS-CoV-2 is rare, the virus has been associated with placental complications and increased...

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Bibliographic Details
Main Authors: Athina Samara, Conrado Milani Coutinho, Paul T. Heath, Asma Khalil
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Pediatrics
Subjects:
SARS-CoV2
congenital heart defects
maternal infection
COVID-19
CHD
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2025.1643423/full
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