Modification of the laser correlation spectrometer for analysis of biological fluids
Modifications of the laser correlation spectrometer system developed for the analysis of biological fluids have been discussed. Parameters of the proposed laser correlation spectrometer allowing to determine the sizes of nanoparticles in biological fluids, which are highly polydisperse solutions, to...
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| Format: | Article |
| Language: | English |
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Kazan Federal University
2018-03-01
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| Series: | Учёные записки Казанского университета: Серия Физико-математические науки |
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| Online Access: | https://kpfu.ru/modification-of-the-laser-correlation_342717.html |
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| _version_ | 1850038590476648448 |
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| author | E.N. Velichko E.K. Nepomnyashchaya E.T. Aksenov |
| author_facet | E.N. Velichko E.K. Nepomnyashchaya E.T. Aksenov |
| author_sort | E.N. Velichko |
| collection | DOAJ |
| description | Modifications of the laser correlation spectrometer system developed for the analysis of biological fluids have been discussed. Parameters of the proposed laser correlation spectrometer allowing to determine the sizes of nanoparticles in biological fluids, which are highly polydisperse solutions, to within 0.5 nm have been presented. We have explained the use of optical fiber in the spectrometer circuit as a system for collecting scattered radiation. Furthermore, we calculated the parameters of the discretization of the registered signals. It is for the correct selection of the ADC-converter. The results of the experiment showing significant differences in the size composition of donor blood serum proteins have been presented. Thus, the possibility for analyzing the composition of the blood serum of various donors and for obtaining diagnostic data has been proved. |
| format | Article |
| id | doaj-art-1c4e42379d6c443793e43d3299ec9ebe |
| institution | DOAJ |
| issn | 2541-7746 2500-2198 |
| language | English |
| publishDate | 2018-03-01 |
| publisher | Kazan Federal University |
| record_format | Article |
| series | Учёные записки Казанского университета: Серия Физико-математические науки |
| spelling | doaj-art-1c4e42379d6c443793e43d3299ec9ebe2025-08-20T02:56:33ZengKazan Federal UniversityУчёные записки Казанского университета: Серия Физико-математические науки2541-77462500-21982018-03-0116015160Modification of the laser correlation spectrometer for analysis of biological fluidsE.N. Velichko0E.K. Nepomnyashchaya1E.T. Aksenov2Peter the Great St. Petersburg Polytechnic University, St. Petersburg, 195251 RussiaPeter the Great St. Petersburg Polytechnic University, St. Petersburg, 195251 RussiaPeter the Great St. Petersburg Polytechnic University, St. Petersburg, 195251 RussiaModifications of the laser correlation spectrometer system developed for the analysis of biological fluids have been discussed. Parameters of the proposed laser correlation spectrometer allowing to determine the sizes of nanoparticles in biological fluids, which are highly polydisperse solutions, to within 0.5 nm have been presented. We have explained the use of optical fiber in the spectrometer circuit as a system for collecting scattered radiation. Furthermore, we calculated the parameters of the discretization of the registered signals. It is for the correct selection of the ADC-converter. The results of the experiment showing significant differences in the size composition of donor blood serum proteins have been presented. Thus, the possibility for analyzing the composition of the blood serum of various donors and for obtaining diagnostic data has been proved.https://kpfu.ru/modification-of-the-laser-correlation_342717.htmllaser correlation spectroscopyimmune systemmolecular analysisblood serum |
| spellingShingle | E.N. Velichko E.K. Nepomnyashchaya E.T. Aksenov Modification of the laser correlation spectrometer for analysis of biological fluids Учёные записки Казанского университета: Серия Физико-математические науки laser correlation spectroscopy immune system molecular analysis blood serum |
| title | Modification of the laser correlation spectrometer for analysis of biological fluids |
| title_full | Modification of the laser correlation spectrometer for analysis of biological fluids |
| title_fullStr | Modification of the laser correlation spectrometer for analysis of biological fluids |
| title_full_unstemmed | Modification of the laser correlation spectrometer for analysis of biological fluids |
| title_short | Modification of the laser correlation spectrometer for analysis of biological fluids |
| title_sort | modification of the laser correlation spectrometer for analysis of biological fluids |
| topic | laser correlation spectroscopy immune system molecular analysis blood serum |
| url | https://kpfu.ru/modification-of-the-laser-correlation_342717.html |
| work_keys_str_mv | AT envelichko modificationofthelasercorrelationspectrometerforanalysisofbiologicalfluids AT eknepomnyashchaya modificationofthelasercorrelationspectrometerforanalysisofbiologicalfluids AT etaksenov modificationofthelasercorrelationspectrometerforanalysisofbiologicalfluids |