A Multifunctional Cobalt‐Containing Implant for Treating Biofilm Infections and Promoting Osteointegration in Infected Bone Defects Through Macrophage‐Mediated Immunomodulation

A Multifunctional Cobalt‐Containing Implant for Treating Biofilm Infections and Promoting Osteointegration in Infected Bone Defects Through Macrophage‐Mediated Immunomodulation

Abstract Treating bone infections and ensuring bone recovery is one of the major global problems facing modern orthopedics. Prolonged antibiotic use may increase the risk of antimicrobial resistance, and inflammation caused by biofilms can obstruct tissue healing, making bone infection treatment eve...

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Bibliographic Details
Main Authors: Nongyang Yan, Hao Zhou, Penghe Jin, Tengfei Li, Qi Liu, Hao Ning, Zhixin Ma, Linfei Feng, Tao Jin, Youwen Deng, Zhengwei Wu
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
bone infection therapy
cobalt‐containing implants
immunomodulation
osteogenic differentiation
plasma immersion ion implantation (PIII)
Online Access:https://doi.org/10.1002/advs.202409200
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