Cephalopod proteins for bioinspired and sustainable biomaterials design

Nature offers a boundless source of inspiration for designing bio-inspired technologies and advanced materials. Cephalopods, including octopuses, squids, and cuttlefish, exhibit remarkable biological adaptations, such as dynamic camouflage for predator evasion and communication, as well as robust pr...

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Main Authors: Iana Lychko, Inês Padrão, Afonso Vicente Eva, Catarina Alexandra Oliveira Domingos, Henrique Miguel Aljustrel da Costa, Ana Margarida Gonçalves Carvalho Dias, Ana Cecília Afonso Roque
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Materials Today Bio
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425002029
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author Iana Lychko
Inês Padrão
Afonso Vicente Eva
Catarina Alexandra Oliveira Domingos
Henrique Miguel Aljustrel da Costa
Ana Margarida Gonçalves Carvalho Dias
Ana Cecília Afonso Roque
author_facet Iana Lychko
Inês Padrão
Afonso Vicente Eva
Catarina Alexandra Oliveira Domingos
Henrique Miguel Aljustrel da Costa
Ana Margarida Gonçalves Carvalho Dias
Ana Cecília Afonso Roque
author_sort Iana Lychko
collection DOAJ
description Nature offers a boundless source of inspiration for designing bio-inspired technologies and advanced materials. Cephalopods, including octopuses, squids, and cuttlefish, exhibit remarkable biological adaptations, such as dynamic camouflage for predator evasion and communication, as well as robust prey-capturing tools, including beaks and sucker-ring teeth that operate under extreme mechanical stresses in aqueous environments. Central to these remarkable traits are structural proteins that serve as versatile polymeric materials. From a materials science perspective, proteins present unique opportunities due to their genetically encoded sequences, enabling access to a diversity of sequences and precise control over polymer composition and properties. This intrinsic programmability allows scalable, environmentally sustainable production through recombinant biotechnology, in contrast to petroleum-derived polymers. This review highlights recent advances in understanding cephalopod-specific proteins, emphasizing their potential for creating next-generation bioengineered materials and driving sustainable innovation in biomaterials science.
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issn 2590-0064
language English
publishDate 2025-04-01
publisher Elsevier
record_format Article
series Materials Today Bio
spelling doaj-art-1c20a136d2324b8183d17697449e68e92025-08-20T02:47:49ZengElsevierMaterials Today Bio2590-00642025-04-013110164410.1016/j.mtbio.2025.101644Cephalopod proteins for bioinspired and sustainable biomaterials designIana Lychko0Inês Padrão1Afonso Vicente Eva2Catarina Alexandra Oliveira Domingos3Henrique Miguel Aljustrel da Costa4Ana Margarida Gonçalves Carvalho Dias5Ana Cecília Afonso Roque6UCIBIO – Applied Molecular Biosciences Unit, Department of Chemistry, School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal; Associate Laboratory I4HB – Institute for Health and Bioeconomy, School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, PortugalUCIBIO – Applied Molecular Biosciences Unit, Department of Chemistry, School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal; Associate Laboratory I4HB – Institute for Health and Bioeconomy, School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, PortugalUCIBIO – Applied Molecular Biosciences Unit, Department of Chemistry, School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal; Associate Laboratory I4HB – Institute for Health and Bioeconomy, School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, PortugalUCIBIO – Applied Molecular Biosciences Unit, Department of Chemistry, School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal; Associate Laboratory I4HB – Institute for Health and Bioeconomy, School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, PortugalUCIBIO – Applied Molecular Biosciences Unit, Department of Chemistry, School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal; Associate Laboratory I4HB – Institute for Health and Bioeconomy, School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, PortugalUCIBIO – Applied Molecular Biosciences Unit, Department of Chemistry, School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal; Associate Laboratory I4HB – Institute for Health and Bioeconomy, School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, PortugalUCIBIO – Applied Molecular Biosciences Unit, Department of Chemistry, School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal; Associate Laboratory I4HB – Institute for Health and Bioeconomy, School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal; Corresponding author. UCIBIO – Applied Molecular Biosciences Unit, Department of Chemistry, School of Science and Technology, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal.Nature offers a boundless source of inspiration for designing bio-inspired technologies and advanced materials. Cephalopods, including octopuses, squids, and cuttlefish, exhibit remarkable biological adaptations, such as dynamic camouflage for predator evasion and communication, as well as robust prey-capturing tools, including beaks and sucker-ring teeth that operate under extreme mechanical stresses in aqueous environments. Central to these remarkable traits are structural proteins that serve as versatile polymeric materials. From a materials science perspective, proteins present unique opportunities due to their genetically encoded sequences, enabling access to a diversity of sequences and precise control over polymer composition and properties. This intrinsic programmability allows scalable, environmentally sustainable production through recombinant biotechnology, in contrast to petroleum-derived polymers. This review highlights recent advances in understanding cephalopod-specific proteins, emphasizing their potential for creating next-generation bioengineered materials and driving sustainable innovation in biomaterials science.http://www.sciencedirect.com/science/article/pii/S2590006425002029Protein-based materialsCephalopodsReflectinsHistidine-binding proteinsSuckerins
spellingShingle Iana Lychko
Inês Padrão
Afonso Vicente Eva
Catarina Alexandra Oliveira Domingos
Henrique Miguel Aljustrel da Costa
Ana Margarida Gonçalves Carvalho Dias
Ana Cecília Afonso Roque
Cephalopod proteins for bioinspired and sustainable biomaterials design
Materials Today Bio
Protein-based materials
Cephalopods
Reflectins
Histidine-binding proteins
Suckerins
title Cephalopod proteins for bioinspired and sustainable biomaterials design
title_full Cephalopod proteins for bioinspired and sustainable biomaterials design
title_fullStr Cephalopod proteins for bioinspired and sustainable biomaterials design
title_full_unstemmed Cephalopod proteins for bioinspired and sustainable biomaterials design
title_short Cephalopod proteins for bioinspired and sustainable biomaterials design
title_sort cephalopod proteins for bioinspired and sustainable biomaterials design
topic Protein-based materials
Cephalopods
Reflectins
Histidine-binding proteins
Suckerins
url http://www.sciencedirect.com/science/article/pii/S2590006425002029
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AT henriquemiguelaljustreldacosta cephalopodproteinsforbioinspiredandsustainablebiomaterialsdesign
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