Preparation of La2Sn2O7, Mg2SnO4, and MgSn(OH)6 and their antiviral/antibacterial activities

Abstract In order to develop inorganic antibacterial and antiviral materials that function in the dark, we synthesized La2Sn2O7, Mg2SnO4, and MgSn(OH)6, which are compounds of La2O3 and MgO, which have solid basicity, and SnO2, which has the Mars-van Krevelen (MvK) mechanism. After obtaining each sa...

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Main Authors: Ryuju Kiribayashi, Kayano Sunada, Yasuhide Mochizuki, Toshihiro Isobe, Keiichi Kobayashi, Takeshi Nagai, Hitoshi Ishiguro, Akira Nakajima
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Journal of Materials Science: Materials in Medicine
Online Access:https://doi.org/10.1007/s10856-025-06921-3
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author Ryuju Kiribayashi
Kayano Sunada
Yasuhide Mochizuki
Toshihiro Isobe
Keiichi Kobayashi
Takeshi Nagai
Hitoshi Ishiguro
Akira Nakajima
author_facet Ryuju Kiribayashi
Kayano Sunada
Yasuhide Mochizuki
Toshihiro Isobe
Keiichi Kobayashi
Takeshi Nagai
Hitoshi Ishiguro
Akira Nakajima
author_sort Ryuju Kiribayashi
collection DOAJ
description Abstract In order to develop inorganic antibacterial and antiviral materials that function in the dark, we synthesized La2Sn2O7, Mg2SnO4, and MgSn(OH)6, which are compounds of La2O3 and MgO, which have solid basicity, and SnO2, which has the Mars-van Krevelen (MvK) mechanism. After obtaining each sample as a single-phase white powder through hydrothermal or coprecipitation method, their antibacterial and antiviral activities were evaluated with reference to ISO procedures in the dark for bacteria and viruses with different characteristics. The dependence of activity on the evaluation method suggested that, except for Mg2SnO4, the proximity or contact of the viruses or bacteria to the sample surface played an important role in activity. Comparison of the activity of each sample with those of the simple oxides of constituent elements, La2O3, MgO, and SnO2, clarified that pH, solid basicity, phosphate affinity, and the MvK mechanism contribute to antibacterial and antiviral activity. The extent of these contributions varied depending on the sample. The study results revealed that La2Sn2O7 not only exhibits high antibacterial and antiviral activity against bacteria and viruses in the dark; it also has the ability to decompose organic dyes under UV irradiation. This material might be used as a newly developed environmental purification material providing continuous antibacterial and antiviral effects day and night, able to clean surfaces during UV light exposure. Graphical Abstract
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publishDate 2025-08-01
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series Journal of Materials Science: Materials in Medicine
spelling doaj-art-1c1a9d5b912e4092b94696bc89975d412025-08-20T03:42:34ZengSpringerJournal of Materials Science: Materials in Medicine1573-48382025-08-0136111410.1007/s10856-025-06921-3Preparation of La2Sn2O7, Mg2SnO4, and MgSn(OH)6 and their antiviral/antibacterial activitiesRyuju Kiribayashi0Kayano Sunada1Yasuhide Mochizuki2Toshihiro Isobe3Keiichi Kobayashi4Takeshi Nagai5Hitoshi Ishiguro6Akira Nakajima7Department of Materials Science and Engineering, School of Materials and Chemical Technology, Institute of Science TokyoLife Science Technology Project, Kanagawa Institute of Industrial Science and TechnologyDepartment of Materials Science and Engineering, School of Materials and Chemical Technology, Institute of Science TokyoDepartment of Materials Science and Engineering, School of Materials and Chemical Technology, Institute of Science TokyoLife Science Technology Project, Kanagawa Institute of Industrial Science and TechnologyLife Science Technology Project, Kanagawa Institute of Industrial Science and TechnologyLife Science Technology Project, Kanagawa Institute of Industrial Science and TechnologyDepartment of Materials Science and Engineering, School of Materials and Chemical Technology, Institute of Science TokyoAbstract In order to develop inorganic antibacterial and antiviral materials that function in the dark, we synthesized La2Sn2O7, Mg2SnO4, and MgSn(OH)6, which are compounds of La2O3 and MgO, which have solid basicity, and SnO2, which has the Mars-van Krevelen (MvK) mechanism. After obtaining each sample as a single-phase white powder through hydrothermal or coprecipitation method, their antibacterial and antiviral activities were evaluated with reference to ISO procedures in the dark for bacteria and viruses with different characteristics. The dependence of activity on the evaluation method suggested that, except for Mg2SnO4, the proximity or contact of the viruses or bacteria to the sample surface played an important role in activity. Comparison of the activity of each sample with those of the simple oxides of constituent elements, La2O3, MgO, and SnO2, clarified that pH, solid basicity, phosphate affinity, and the MvK mechanism contribute to antibacterial and antiviral activity. The extent of these contributions varied depending on the sample. The study results revealed that La2Sn2O7 not only exhibits high antibacterial and antiviral activity against bacteria and viruses in the dark; it also has the ability to decompose organic dyes under UV irradiation. This material might be used as a newly developed environmental purification material providing continuous antibacterial and antiviral effects day and night, able to clean surfaces during UV light exposure. Graphical Abstracthttps://doi.org/10.1007/s10856-025-06921-3
spellingShingle Ryuju Kiribayashi
Kayano Sunada
Yasuhide Mochizuki
Toshihiro Isobe
Keiichi Kobayashi
Takeshi Nagai
Hitoshi Ishiguro
Akira Nakajima
Preparation of La2Sn2O7, Mg2SnO4, and MgSn(OH)6 and their antiviral/antibacterial activities
Journal of Materials Science: Materials in Medicine
title Preparation of La2Sn2O7, Mg2SnO4, and MgSn(OH)6 and their antiviral/antibacterial activities
title_full Preparation of La2Sn2O7, Mg2SnO4, and MgSn(OH)6 and their antiviral/antibacterial activities
title_fullStr Preparation of La2Sn2O7, Mg2SnO4, and MgSn(OH)6 and their antiviral/antibacterial activities
title_full_unstemmed Preparation of La2Sn2O7, Mg2SnO4, and MgSn(OH)6 and their antiviral/antibacterial activities
title_short Preparation of La2Sn2O7, Mg2SnO4, and MgSn(OH)6 and their antiviral/antibacterial activities
title_sort preparation of la2sn2o7 mg2sno4 and mgsn oh 6 and their antiviral antibacterial activities
url https://doi.org/10.1007/s10856-025-06921-3
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