Zearalenone Exposure Damages Skeletal Muscle Through Oxidative Stress and Is Alleviated by Glutathione, Nicotinamide Mononucleotide, and Melatonin

Zearalenone Exposure Damages Skeletal Muscle Through Oxidative Stress and Is Alleviated by Glutathione, Nicotinamide Mononucleotide, and Melatonin

Zearalenone (ZEN), a mycotoxin, is toxic to skeletal muscle, and the solution to alleviate its damage remains unknown. Here, we analyzed the toxic effect of ZEN on muscle and the mitigation of antioxidants (GSH, NMN, and melatonin) for this toxicity. The results showed that 0.02 mmol/L ZEN inhibited...

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Bibliographic Details
Main Authors: Dandan Li, Wei Fu, Jiyue Zhang, Yaqiu Lin, Xianrong Xiong, Jian Li, Yan Xiong
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Antioxidants
Subjects:
zearalenone
toxicity
skeletal muscle
antioxidant
muscle fiber
Online Access:https://www.mdpi.com/2076-3921/14/5/528
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