Retrospective analysis of clinical and epidemiological characteristics of Chinese cobra bites in a South China emergency department

Abstract In China, it is estimated that over 100,000 snakebite incidents occur each year, significantly endangering human life. This study retrospectively analyzed the treatment data of Chinese cobra bite patients in a Chinese hospital from 2010 to July 2017. It was found that local necrosis typical...

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Main Authors: Zhou Huang, Xiao-dan Lv, Dong-Ling Huang, Fan Wang, Wan-Xia Wei, Guo-Dong Pang, Wei Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-04204-z
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author Zhou Huang
Xiao-dan Lv
Dong-Ling Huang
Fan Wang
Wan-Xia Wei
Guo-Dong Pang
Wei Wang
author_facet Zhou Huang
Xiao-dan Lv
Dong-Ling Huang
Fan Wang
Wan-Xia Wei
Guo-Dong Pang
Wei Wang
author_sort Zhou Huang
collection DOAJ
description Abstract In China, it is estimated that over 100,000 snakebite incidents occur each year, significantly endangering human life. This study retrospectively analyzed the treatment data of Chinese cobra bite patients in a Chinese hospital from 2010 to July 2017. It was found that local necrosis typically occurs after a Chinese cobra bite, and effective treatment involves removal of the necrotic tissue and facilitating wound healing with anti-infection measures. The extent of local damage after the bite was correlated with creatine kinase levels. In addition, early administration of Chinese cobra antivenom was beneficial as it alleviated local necrosis and reduced the likelihood of adverse complications. However, under the current treatment protocols, the use or nonuse of Chinese cobra antivenom does not significantly impact survival outcomes.
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spelling doaj-art-1bfd98fa31f54fe9a96d6d65ecd8e9cd2025-08-20T03:03:36ZengNature PortfolioScientific Reports2045-23222025-07-0115111110.1038/s41598-025-04204-zRetrospective analysis of clinical and epidemiological characteristics of Chinese cobra bites in a South China emergency departmentZhou Huang0Xiao-dan Lv1Dong-Ling Huang2Fan Wang3Wan-Xia Wei4Guo-Dong Pang5Wei Wang6Department of Emergency, The First Affiliated Hospital of Guangxi Medical UniversityDepartment of Emergency, The First Affiliated Hospital of Guangxi Medical UniversityDepartment of Emergency, The First Affiliated Hospital of Guangxi Medical UniversityDepartment of Emergency, The First Affiliated Hospital of Guangxi Medical UniversityDepartment of Emergency, The First Affiliated Hospital of Guangxi Medical UniversityDepartment of Emergency, The First Affiliated Hospital of Guangxi Medical UniversityDepartment of Emergency, The First Affiliated Hospital of Guangxi Medical UniversityAbstract In China, it is estimated that over 100,000 snakebite incidents occur each year, significantly endangering human life. This study retrospectively analyzed the treatment data of Chinese cobra bite patients in a Chinese hospital from 2010 to July 2017. It was found that local necrosis typically occurs after a Chinese cobra bite, and effective treatment involves removal of the necrotic tissue and facilitating wound healing with anti-infection measures. The extent of local damage after the bite was correlated with creatine kinase levels. In addition, early administration of Chinese cobra antivenom was beneficial as it alleviated local necrosis and reduced the likelihood of adverse complications. However, under the current treatment protocols, the use or nonuse of Chinese cobra antivenom does not significantly impact survival outcomes.https://doi.org/10.1038/s41598-025-04204-zSnakebiteChinese cobraVenomAntivenom
spellingShingle Zhou Huang
Xiao-dan Lv
Dong-Ling Huang
Fan Wang
Wan-Xia Wei
Guo-Dong Pang
Wei Wang
Retrospective analysis of clinical and epidemiological characteristics of Chinese cobra bites in a South China emergency department
Scientific Reports
Snakebite
Chinese cobra
Venom
Antivenom
title Retrospective analysis of clinical and epidemiological characteristics of Chinese cobra bites in a South China emergency department
title_full Retrospective analysis of clinical and epidemiological characteristics of Chinese cobra bites in a South China emergency department
title_fullStr Retrospective analysis of clinical and epidemiological characteristics of Chinese cobra bites in a South China emergency department
title_full_unstemmed Retrospective analysis of clinical and epidemiological characteristics of Chinese cobra bites in a South China emergency department
title_short Retrospective analysis of clinical and epidemiological characteristics of Chinese cobra bites in a South China emergency department
title_sort retrospective analysis of clinical and epidemiological characteristics of chinese cobra bites in a south china emergency department
topic Snakebite
Chinese cobra
Venom
Antivenom
url https://doi.org/10.1038/s41598-025-04204-z
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