Protocol- Comprehensive Care Package to reduce deaths among adult persons diagnosed with Tuberculosis in Kerala, India (CCp-K)-An implementation project
This implementation project aims to reduce TB mortality by at least 25% through early triaging and integrated management of co-morbidities in Kerala, India. The package will be implemented across Kerala’s public health facilities, targeting all adult TB patients for systematic triaging for severe il...
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Elsevier
2025-12-01
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| Series: | MethodsX |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2215016125004169 |
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| author | Raman Swathy Vaman Kalaiselvi Selvaraj Dina Nair Abey Sushan Aparna Mohan Krishna Devadhas Sulochana Jeen Melfha Arun Paramarthalingom Vijayalekshmi Vyas Sukumaran Naveen Anaswara Sujith Sukumaran Annadurai Jeyakumar Rakesh Purushothama Bhat Susheela Rajaram Kizhakkekandiyil Hemant Deepak Shewade |
| author_facet | Raman Swathy Vaman Kalaiselvi Selvaraj Dina Nair Abey Sushan Aparna Mohan Krishna Devadhas Sulochana Jeen Melfha Arun Paramarthalingom Vijayalekshmi Vyas Sukumaran Naveen Anaswara Sujith Sukumaran Annadurai Jeyakumar Rakesh Purushothama Bhat Susheela Rajaram Kizhakkekandiyil Hemant Deepak Shewade |
| author_sort | Raman Swathy Vaman |
| collection | DOAJ |
| description | This implementation project aims to reduce TB mortality by at least 25% through early triaging and integrated management of co-morbidities in Kerala, India. The package will be implemented across Kerala’s public health facilities, targeting all adult TB patients for systematic triaging for severe illness, uncontrolled diabetes mellitus, alcohol dependence, and tobacco dependence. Triage-positive individuals will be referred for comprehensive assessment and inpatient care to nodal treatment centres. This research will follow a mixed-methods approach with quantitative components assessing feasibility, burden, and programmatic outcomes, and qualitative interviews exploring facilitators and barriers. Triaging will be integrated into routine workflows with healthcare worker training and system monitoring using customized indicators. If found feasible and effective in improving programmatic outcomes such as early triaging and inpatient referral, this model offers potential for scale-up across India to reduce preventable TB deaths through differentiated care and targeted comorbidity management.• Implements a comprehensive care package to reduce TB deaths through early triaging and comorbidity management• Leverages existing public health infrastructure to deliver enhanced TB care within routine programme settings |
| format | Article |
| id | doaj-art-1bfa084d5c3d40de9d48b9fd38e29935 |
| institution | Kabale University |
| issn | 2215-0161 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | MethodsX |
| spelling | doaj-art-1bfa084d5c3d40de9d48b9fd38e299352025-08-24T05:12:49ZengElsevierMethodsX2215-01612025-12-011510357210.1016/j.mex.2025.103572Protocol- Comprehensive Care Package to reduce deaths among adult persons diagnosed with Tuberculosis in Kerala, India (CCp-K)-An implementation projectRaman Swathy Vaman0Kalaiselvi Selvaraj1Dina Nair2Abey Sushan3Aparna Mohan4Krishna Devadhas Sulochana5Jeen Melfha6Arun Paramarthalingom Vijayalekshmi7Vyas Sukumaran8Naveen Anaswara9Sujith Sukumaran10Annadurai Jeyakumar11Rakesh Purushothama Bhat Susheela12Rajaram Kizhakkekandiyil13Hemant Deepak Shewade14Department of Health and Family Welfare, Government of Kerala, India; Corresponding author.All India Institute of Medical Sciences, Madurai, Tamil Nadu, IndiaICMR- National Institute for Research in Tuberculosis, Chennai, Tamil Nadu, IndiaDepartment of Health and Family Welfare, Government of Kerala, IndiaWHO NTEP division, Kerala, IndiaDepartment of Health and Family Welfare, Government of Kerala, IndiaICMR- National Institute of Epidemiology, Chennai, Tamil Nadu, IndiaDepartment of Health and Family Welfare, Government of Kerala, IndiaDepartment of Health and Family Welfare, Government of Kerala, IndiaDepartment of Health and Family Welfare, Government of Kerala, IndiaDepartment of Health and Family Welfare, Government of Kerala, IndiaICMR- National Institute of Epidemiology, Chennai, Tamil Nadu, IndiaThe Union, New Delhi, IndiaDepartment of Health and Family Welfare, Government of Kerala, IndiaICMR- National Institute of Epidemiology, Chennai, Tamil Nadu, IndiaThis implementation project aims to reduce TB mortality by at least 25% through early triaging and integrated management of co-morbidities in Kerala, India. The package will be implemented across Kerala’s public health facilities, targeting all adult TB patients for systematic triaging for severe illness, uncontrolled diabetes mellitus, alcohol dependence, and tobacco dependence. Triage-positive individuals will be referred for comprehensive assessment and inpatient care to nodal treatment centres. This research will follow a mixed-methods approach with quantitative components assessing feasibility, burden, and programmatic outcomes, and qualitative interviews exploring facilitators and barriers. Triaging will be integrated into routine workflows with healthcare worker training and system monitoring using customized indicators. If found feasible and effective in improving programmatic outcomes such as early triaging and inpatient referral, this model offers potential for scale-up across India to reduce preventable TB deaths through differentiated care and targeted comorbidity management.• Implements a comprehensive care package to reduce TB deaths through early triaging and comorbidity management• Leverages existing public health infrastructure to deliver enhanced TB care within routine programme settingshttp://www.sciencedirect.com/science/article/pii/S2215016125004169TuberculosisImplementation researchOperational researchIndiaDifferentiated TB careTB mortality |
| spellingShingle | Raman Swathy Vaman Kalaiselvi Selvaraj Dina Nair Abey Sushan Aparna Mohan Krishna Devadhas Sulochana Jeen Melfha Arun Paramarthalingom Vijayalekshmi Vyas Sukumaran Naveen Anaswara Sujith Sukumaran Annadurai Jeyakumar Rakesh Purushothama Bhat Susheela Rajaram Kizhakkekandiyil Hemant Deepak Shewade Protocol- Comprehensive Care Package to reduce deaths among adult persons diagnosed with Tuberculosis in Kerala, India (CCp-K)-An implementation project MethodsX Tuberculosis Implementation research Operational research India Differentiated TB care TB mortality |
| title | Protocol- Comprehensive Care Package to reduce deaths among adult persons diagnosed with Tuberculosis in Kerala, India (CCp-K)-An implementation project |
| title_full | Protocol- Comprehensive Care Package to reduce deaths among adult persons diagnosed with Tuberculosis in Kerala, India (CCp-K)-An implementation project |
| title_fullStr | Protocol- Comprehensive Care Package to reduce deaths among adult persons diagnosed with Tuberculosis in Kerala, India (CCp-K)-An implementation project |
| title_full_unstemmed | Protocol- Comprehensive Care Package to reduce deaths among adult persons diagnosed with Tuberculosis in Kerala, India (CCp-K)-An implementation project |
| title_short | Protocol- Comprehensive Care Package to reduce deaths among adult persons diagnosed with Tuberculosis in Kerala, India (CCp-K)-An implementation project |
| title_sort | protocol comprehensive care package to reduce deaths among adult persons diagnosed with tuberculosis in kerala india ccp k an implementation project |
| topic | Tuberculosis Implementation research Operational research India Differentiated TB care TB mortality |
| url | http://www.sciencedirect.com/science/article/pii/S2215016125004169 |
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