Expedient Protocols for the Installation of Pyrimidine Based Privileged Templates on 2-Position of Pyrrolo[2,1-c][1,4]-benzodiazepine Nucleus Linked Through a p-phenoxyl Spacer
Exceedingly facile single step expedient protocols based on the versatility and reactivity of corresponding intermediates : [2-(dimethylaminomethylene) ketone] (5) and chalcone (6), derived from 2-(p-acetyl phenoxyl) substituted analogue of pyrrolo[2,1-c][1,4]-benzodiazepine (4), have been developed...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
|
| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2012/629414 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832555372676644864 |
|---|---|
| author | Anshu Agarwal Meenakshi Sharma Meenakshi Agrawal D. Kishore |
| author_facet | Anshu Agarwal Meenakshi Sharma Meenakshi Agrawal D. Kishore |
| author_sort | Anshu Agarwal |
| collection | DOAJ |
| description | Exceedingly facile single step expedient protocols based on the versatility and reactivity of corresponding intermediates : [2-(dimethylaminomethylene) ketone] (5) and chalcone (6), derived from 2-(p-acetyl phenoxyl) substituted analogue of pyrrolo[2,1-c][1,4]-benzodiazepine (4), have been developed to provide an easy installation of the pyrimidine based privileged templates at 2-position of pyrrolo[2,1-c][1,4]-benzodiazepine through a p-phenoxyl spacer, by utilizing the synthetic strategy depicted in schemes-1 and 2. |
| format | Article |
| id | doaj-art-1bf5bc3d1e574d27b2d3b7104f5c1fa9 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-1bf5bc3d1e574d27b2d3b7104f5c1fa92025-02-03T05:48:20ZengWileyE-Journal of Chemistry0973-49452090-98102012-01-01931305131210.1155/2012/629414Expedient Protocols for the Installation of Pyrimidine Based Privileged Templates on 2-Position of Pyrrolo[2,1-c][1,4]-benzodiazepine Nucleus Linked Through a p-phenoxyl SpacerAnshu Agarwal0Meenakshi Sharma1Meenakshi Agrawal2D. Kishore3Department of Chemistry, Banasthali University, Banasthali (RAJ. 304022), IndiaDepartment of Chemistry, Banasthali University, Banasthali (RAJ. 304022), IndiaDepartment of Chemistry, Banasthali University, Banasthali (RAJ. 304022), IndiaDepartment of Chemistry, Banasthali University, Banasthali (RAJ. 304022), IndiaExceedingly facile single step expedient protocols based on the versatility and reactivity of corresponding intermediates : [2-(dimethylaminomethylene) ketone] (5) and chalcone (6), derived from 2-(p-acetyl phenoxyl) substituted analogue of pyrrolo[2,1-c][1,4]-benzodiazepine (4), have been developed to provide an easy installation of the pyrimidine based privileged templates at 2-position of pyrrolo[2,1-c][1,4]-benzodiazepine through a p-phenoxyl spacer, by utilizing the synthetic strategy depicted in schemes-1 and 2.http://dx.doi.org/10.1155/2012/629414 |
| spellingShingle | Anshu Agarwal Meenakshi Sharma Meenakshi Agrawal D. Kishore Expedient Protocols for the Installation of Pyrimidine Based Privileged Templates on 2-Position of Pyrrolo[2,1-c][1,4]-benzodiazepine Nucleus Linked Through a p-phenoxyl Spacer E-Journal of Chemistry |
| title | Expedient Protocols for the Installation of Pyrimidine Based Privileged Templates on 2-Position of Pyrrolo[2,1-c][1,4]-benzodiazepine Nucleus Linked Through a p-phenoxyl Spacer |
| title_full | Expedient Protocols for the Installation of Pyrimidine Based Privileged Templates on 2-Position of Pyrrolo[2,1-c][1,4]-benzodiazepine Nucleus Linked Through a p-phenoxyl Spacer |
| title_fullStr | Expedient Protocols for the Installation of Pyrimidine Based Privileged Templates on 2-Position of Pyrrolo[2,1-c][1,4]-benzodiazepine Nucleus Linked Through a p-phenoxyl Spacer |
| title_full_unstemmed | Expedient Protocols for the Installation of Pyrimidine Based Privileged Templates on 2-Position of Pyrrolo[2,1-c][1,4]-benzodiazepine Nucleus Linked Through a p-phenoxyl Spacer |
| title_short | Expedient Protocols for the Installation of Pyrimidine Based Privileged Templates on 2-Position of Pyrrolo[2,1-c][1,4]-benzodiazepine Nucleus Linked Through a p-phenoxyl Spacer |
| title_sort | expedient protocols for the installation of pyrimidine based privileged templates on 2 position of pyrrolo 2 1 c 1 4 benzodiazepine nucleus linked through a p phenoxyl spacer |
| url | http://dx.doi.org/10.1155/2012/629414 |
| work_keys_str_mv | AT anshuagarwal expedientprotocolsfortheinstallationofpyrimidinebasedprivilegedtemplateson2positionofpyrrolo21c14benzodiazepinenucleuslinkedthroughapphenoxylspacer AT meenakshisharma expedientprotocolsfortheinstallationofpyrimidinebasedprivilegedtemplateson2positionofpyrrolo21c14benzodiazepinenucleuslinkedthroughapphenoxylspacer AT meenakshiagrawal expedientprotocolsfortheinstallationofpyrimidinebasedprivilegedtemplateson2positionofpyrrolo21c14benzodiazepinenucleuslinkedthroughapphenoxylspacer AT dkishore expedientprotocolsfortheinstallationofpyrimidinebasedprivilegedtemplateson2positionofpyrrolo21c14benzodiazepinenucleuslinkedthroughapphenoxylspacer |