Evaluating plasma biomarkers NfL, GFAP, GDF15, and FGF21 as indicators of disease severity in Charcot–Marie Tooth patients

Evaluating plasma biomarkers NfL, GFAP, GDF15, and FGF21 as indicators of disease severity in Charcot–Marie Tooth patients

BackgroundCharcot–Marie–Tooth disease (CMT), a slowly advancing hereditary nerve disorder, presents a significant challenge in the medical field. Effective drugs for treatment are lacking, and we struggle to find sensitive markers to track the disease’s severity and progression. In this study, our o...

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Bibliographic Details
Main Authors: Dace Pretkalnina, Elizabete Kenina, Linda Gailite, Dmitrijs Rots, Kaj Blennow, Henrik Zetterberg, Viktorija Kenina
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Neurology
Subjects:
CMT
biomarker
NFL
FGF21
GFAP - glial fibrillary acidic protein
GDF15
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2024.1490024/full
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