The Impact of HIV on Maternal Morbidity in the Pre-HAART Era in Uganda
Objective. To compare maternal morbidity in HIV-infected and uninfected pregnant women. Methods. Major maternal morbidity (severe febrile illness, illnesses requiring hospital admissions, surgical revisions, or illnesses resulting in death) was measured prospectively in a cohort of HIV-infected and...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Journal of Pregnancy |
| Online Access: | http://dx.doi.org/10.1155/2012/508657 |
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| author | Harriet Nuwagaba-Biribonwoha Richard T. Mayon-White Pius Okong Peter Brocklehurst Lucy M. Carpenter |
| author_facet | Harriet Nuwagaba-Biribonwoha Richard T. Mayon-White Pius Okong Peter Brocklehurst Lucy M. Carpenter |
| author_sort | Harriet Nuwagaba-Biribonwoha |
| collection | DOAJ |
| description | Objective. To compare maternal morbidity in HIV-infected and uninfected pregnant women. Methods. Major maternal morbidity (severe febrile illness, illnesses requiring hospital admissions, surgical revisions, or illnesses resulting in death) was measured prospectively in a cohort of HIV-infected and uninfected women followed from 36 weeks of pregnancy to 6 weeks after delivery. Odds ratios of major morbidity and associated factors were examined using logistic regression.
Results. Major morbidity was observed in 46/129 (36%) and 104/390 (27%) of the HIV-infected and HIV-uninfected women, respectively, who remained in followup. In the multivariable analysis, major morbidity was independently associated with HIV infection, adjusted odds ratio (AOR) 1.7 (1.1 to 2.7), nulliparity (AOR 2.0 (1.3 to 3.0)), and lack of, or minimal, formal education (AOR 2.1 (1.1 to 3.8)). Conclusions. HIV was associated with a 70% increase in the odds of major maternal morbidity in these Ugandan mothers. |
| format | Article |
| id | doaj-art-1be8da1fb566400aaf0c42add24f9694 |
| institution | Kabale University |
| issn | 2090-2727 2090-2735 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Pregnancy |
| spelling | doaj-art-1be8da1fb566400aaf0c42add24f96942025-08-20T03:54:51ZengWileyJournal of Pregnancy2090-27272090-27352012-01-01201210.1155/2012/508657508657The Impact of HIV on Maternal Morbidity in the Pre-HAART Era in UgandaHarriet Nuwagaba-Biribonwoha0Richard T. Mayon-White1Pius Okong2Peter Brocklehurst3Lucy M. Carpenter4ICAP, Mailman School of Public Health, Columbia University, P.O. Box 3567, Kampala, UgandaDepartment of Primary Health Care, University of Oxford, Oxford, OX1 2-ET, UKSt. Raphael of St. Francis Hospital, Nsambya, Kampala, UgandaInstitute for Women's Health, University College London, London, WC1E AU, UKDepartment of Public Health, University of Oxford, Oxford, OX3 7LF, UKObjective. To compare maternal morbidity in HIV-infected and uninfected pregnant women. Methods. Major maternal morbidity (severe febrile illness, illnesses requiring hospital admissions, surgical revisions, or illnesses resulting in death) was measured prospectively in a cohort of HIV-infected and uninfected women followed from 36 weeks of pregnancy to 6 weeks after delivery. Odds ratios of major morbidity and associated factors were examined using logistic regression. Results. Major morbidity was observed in 46/129 (36%) and 104/390 (27%) of the HIV-infected and HIV-uninfected women, respectively, who remained in followup. In the multivariable analysis, major morbidity was independently associated with HIV infection, adjusted odds ratio (AOR) 1.7 (1.1 to 2.7), nulliparity (AOR 2.0 (1.3 to 3.0)), and lack of, or minimal, formal education (AOR 2.1 (1.1 to 3.8)). Conclusions. HIV was associated with a 70% increase in the odds of major maternal morbidity in these Ugandan mothers.http://dx.doi.org/10.1155/2012/508657 |
| spellingShingle | Harriet Nuwagaba-Biribonwoha Richard T. Mayon-White Pius Okong Peter Brocklehurst Lucy M. Carpenter The Impact of HIV on Maternal Morbidity in the Pre-HAART Era in Uganda Journal of Pregnancy |
| title | The Impact of HIV on Maternal Morbidity in the Pre-HAART Era in Uganda |
| title_full | The Impact of HIV on Maternal Morbidity in the Pre-HAART Era in Uganda |
| title_fullStr | The Impact of HIV on Maternal Morbidity in the Pre-HAART Era in Uganda |
| title_full_unstemmed | The Impact of HIV on Maternal Morbidity in the Pre-HAART Era in Uganda |
| title_short | The Impact of HIV on Maternal Morbidity in the Pre-HAART Era in Uganda |
| title_sort | impact of hiv on maternal morbidity in the pre haart era in uganda |
| url | http://dx.doi.org/10.1155/2012/508657 |
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