Fever and altered consciousness are not always equal to central nervous system infection: neuroleptic malignant syndrome in a 15-year-old girl

Neuroleptic malignant syndrome, the most serious and potentially fatal side effect of neuroleptics, is characterized by altered consciousness, extrapyramidal symptoms, hyperthermia, elevated plasma creatine phosphoidnase and leukocytosis. In the child and adolescent population, the syndrome m...

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Main Authors: F Unal, S Hizli, H Ozyürek, B Sonuvar
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 1996-10-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/3524
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author F Unal
S Hizli
H Ozyürek
B Sonuvar
author_facet F Unal
S Hizli
H Ozyürek
B Sonuvar
author_sort F Unal
collection DOAJ
description Neuroleptic malignant syndrome, the most serious and potentially fatal side effect of neuroleptics, is characterized by altered consciousness, extrapyramidal symptoms, hyperthermia, elevated plasma creatine phosphoidnase and leukocytosis. In the child and adolescent population, the syndrome may be underrecognized or underreported. We describe a 15-year-old girl who developed neuroleptic malignant syndrome after a single injection of two different neuroleptics. We find the case interesting because the patient's course was unusual, and she was treated successfully with the combination of diazepam and biperiden. Our aim is to discuss several aspects of the syndrome through this case, particularly the problem of recognition.
format Article
id doaj-art-1be89d7f1fcf47c49130e36ebc26ad66
institution DOAJ
issn 0041-4301
2791-6421
language English
publishDate 1996-10-01
publisher Hacettepe University Institute of Child Health
record_format Article
series The Turkish Journal of Pediatrics
spelling doaj-art-1be89d7f1fcf47c49130e36ebc26ad662025-08-20T02:59:41ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64211996-10-01384Fever and altered consciousness are not always equal to central nervous system infection: neuroleptic malignant syndrome in a 15-year-old girlF Unal0S HizliH OzyürekB SonuvarDepartment of Child Psychiatry, Hacettepe University Faculty of Medicine, Ankara. Neuroleptic malignant syndrome, the most serious and potentially fatal side effect of neuroleptics, is characterized by altered consciousness, extrapyramidal symptoms, hyperthermia, elevated plasma creatine phosphoidnase and leukocytosis. In the child and adolescent population, the syndrome may be underrecognized or underreported. We describe a 15-year-old girl who developed neuroleptic malignant syndrome after a single injection of two different neuroleptics. We find the case interesting because the patient's course was unusual, and she was treated successfully with the combination of diazepam and biperiden. Our aim is to discuss several aspects of the syndrome through this case, particularly the problem of recognition. https://turkjpediatr.org/article/view/3524
spellingShingle F Unal
S Hizli
H Ozyürek
B Sonuvar
Fever and altered consciousness are not always equal to central nervous system infection: neuroleptic malignant syndrome in a 15-year-old girl
The Turkish Journal of Pediatrics
title Fever and altered consciousness are not always equal to central nervous system infection: neuroleptic malignant syndrome in a 15-year-old girl
title_full Fever and altered consciousness are not always equal to central nervous system infection: neuroleptic malignant syndrome in a 15-year-old girl
title_fullStr Fever and altered consciousness are not always equal to central nervous system infection: neuroleptic malignant syndrome in a 15-year-old girl
title_full_unstemmed Fever and altered consciousness are not always equal to central nervous system infection: neuroleptic malignant syndrome in a 15-year-old girl
title_short Fever and altered consciousness are not always equal to central nervous system infection: neuroleptic malignant syndrome in a 15-year-old girl
title_sort fever and altered consciousness are not always equal to central nervous system infection neuroleptic malignant syndrome in a 15 year old girl
url https://turkjpediatr.org/article/view/3524
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AT shizli feverandalteredconsciousnessarenotalwaysequaltocentralnervoussysteminfectionneurolepticmalignantsyndromeina15yearoldgirl
AT hozyurek feverandalteredconsciousnessarenotalwaysequaltocentralnervoussysteminfectionneurolepticmalignantsyndromeina15yearoldgirl
AT bsonuvar feverandalteredconsciousnessarenotalwaysequaltocentralnervoussysteminfectionneurolepticmalignantsyndromeina15yearoldgirl