Fever and altered consciousness are not always equal to central nervous system infection: neuroleptic malignant syndrome in a 15-year-old girl

Neuroleptic malignant syndrome, the most serious and potentially fatal side effect of neuroleptics, is characterized by altered consciousness, extrapyramidal symptoms, hyperthermia, elevated plasma creatine phosphoidnase and leukocytosis. In the child and adolescent population, the syndrome m...

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Bibliographic Details
Main Authors: F Unal, S Hizli, H Ozyürek, B Sonuvar
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 1996-10-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/3524
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Summary:Neuroleptic malignant syndrome, the most serious and potentially fatal side effect of neuroleptics, is characterized by altered consciousness, extrapyramidal symptoms, hyperthermia, elevated plasma creatine phosphoidnase and leukocytosis. In the child and adolescent population, the syndrome may be underrecognized or underreported. We describe a 15-year-old girl who developed neuroleptic malignant syndrome after a single injection of two different neuroleptics. We find the case interesting because the patient's course was unusual, and she was treated successfully with the combination of diazepam and biperiden. Our aim is to discuss several aspects of the syndrome through this case, particularly the problem of recognition.
ISSN:0041-4301
2791-6421