Benzophenone Suppression of Quercetin Antioxidant Activity towards Lipids under UV-B Irradiation Regime: Detection by HPLC Chromatography

Quercetin, a well-known flavonoid antioxidant, has been employed to control benzophenone-sensitized peroxidation of the lipid mixture in methanol solution, induced by continuous UV-B irradiation. Surprisingly, the detected quercetin antioxidant activity was almost negligible. The presented data sugg...

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Main Authors: Jelena S. Stanojević, Dejan Z. Marković, Jelena B. Zvezdanović
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2013/761675
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author Jelena S. Stanojević
Dejan Z. Marković
Jelena B. Zvezdanović
author_facet Jelena S. Stanojević
Dejan Z. Marković
Jelena B. Zvezdanović
author_sort Jelena S. Stanojević
collection DOAJ
description Quercetin, a well-known flavonoid antioxidant, has been employed to control benzophenone-sensitized peroxidation of the lipid mixture in methanol solution, induced by continuous UV-B irradiation. Surprisingly, the detected quercetin antioxidant activity was almost negligible. The presented data suggests that the reason is not in its own UV-B-induced degradation but rather in its interrelationship with benzophenone during UV-B stress. On the other side of this relationship, benzophenone anticipated sensitizing role towards lipids; that is, the initiation of lipid peroxidation has been affected as well. These results, obtained by HPLC chromatography, partly confirm but partly relativize to some extent recent results obtained with the same system by spectrophotometric method.
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issn 2090-9063
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publishDate 2013-01-01
publisher Wiley
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spelling doaj-art-1bd43be07e214f13a45cbca781732b862025-08-20T02:01:51ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/761675761675Benzophenone Suppression of Quercetin Antioxidant Activity towards Lipids under UV-B Irradiation Regime: Detection by HPLC ChromatographyJelena S. Stanojević0Dejan Z. Marković1Jelena B. Zvezdanović2Faculty of Technology, University of Niš, 124 Bulevar Oslobodjenja, 16000 Leskovac, SerbiaFaculty of Technology, University of Niš, 124 Bulevar Oslobodjenja, 16000 Leskovac, SerbiaFaculty of Technology, University of Niš, 124 Bulevar Oslobodjenja, 16000 Leskovac, SerbiaQuercetin, a well-known flavonoid antioxidant, has been employed to control benzophenone-sensitized peroxidation of the lipid mixture in methanol solution, induced by continuous UV-B irradiation. Surprisingly, the detected quercetin antioxidant activity was almost negligible. The presented data suggests that the reason is not in its own UV-B-induced degradation but rather in its interrelationship with benzophenone during UV-B stress. On the other side of this relationship, benzophenone anticipated sensitizing role towards lipids; that is, the initiation of lipid peroxidation has been affected as well. These results, obtained by HPLC chromatography, partly confirm but partly relativize to some extent recent results obtained with the same system by spectrophotometric method.http://dx.doi.org/10.1155/2013/761675
spellingShingle Jelena S. Stanojević
Dejan Z. Marković
Jelena B. Zvezdanović
Benzophenone Suppression of Quercetin Antioxidant Activity towards Lipids under UV-B Irradiation Regime: Detection by HPLC Chromatography
Journal of Chemistry
title Benzophenone Suppression of Quercetin Antioxidant Activity towards Lipids under UV-B Irradiation Regime: Detection by HPLC Chromatography
title_full Benzophenone Suppression of Quercetin Antioxidant Activity towards Lipids under UV-B Irradiation Regime: Detection by HPLC Chromatography
title_fullStr Benzophenone Suppression of Quercetin Antioxidant Activity towards Lipids under UV-B Irradiation Regime: Detection by HPLC Chromatography
title_full_unstemmed Benzophenone Suppression of Quercetin Antioxidant Activity towards Lipids under UV-B Irradiation Regime: Detection by HPLC Chromatography
title_short Benzophenone Suppression of Quercetin Antioxidant Activity towards Lipids under UV-B Irradiation Regime: Detection by HPLC Chromatography
title_sort benzophenone suppression of quercetin antioxidant activity towards lipids under uv b irradiation regime detection by hplc chromatography
url http://dx.doi.org/10.1155/2013/761675
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