Glutamine and cancer: metabolism, immune microenvironment, and therapeutic targets

Glutamine and cancer: metabolism, immune microenvironment, and therapeutic targets

Abstract Glutamine is the most abundant amino acid in human serum, and it can provide carbon and nitrogen for biosynthesis, which is crucial for proliferating cells. Moreover, it is widely known that glutamine metabolism is reprogrammed in cancer cells. Many cancer cells undergo metabolic reprogramm...

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Bibliographic Details
Main Authors: Ding Nan, Weiping Yao, Luanluan Huang, Ruiqi Liu, Xiaoyan Chen, Wenjie Xia, Hailong Sheng, Haibo Zhang, Xiaodong Liang, Yanwei Lu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Cell Communication and Signaling
Subjects:
Glutamine metabolism
Cancer
Immune cells
Glutamine antimetabolites
Glutaminase inhibitors
Online Access:https://doi.org/10.1186/s12964-024-02018-6
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