Ankle and Distal Tibia Megaprostheses in Orthopedic Oncology: A Report of Two Cases and Review of the Literature

Background: The distal tibia is one of the rarest sites for the onset of malignant and locally aggressive bone tumors. When diagnosed, these lesions should undergo surgical resection with wide margins to eradicate the disease. In the era of limb-sparing surgery, several reconstructive approaches ha...

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Main Authors: Edoardo Ipponi, Martina Cordoni, Elena Bechini, Fabrizia Gentili, Fabio Cosseddu, Antonio D'Arienzo, Lorenzo Andreani
Format: Article
Language:English
Published: Vilnius University Press 2024-12-01
Series:Acta Medica Lituanica
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Online Access:https://www.zurnalai.vu.lt/AML/article/view/35827
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author Edoardo Ipponi
Martina Cordoni
Elena Bechini
Fabrizia Gentili
Fabio Cosseddu
Antonio D'Arienzo
Lorenzo Andreani
author_facet Edoardo Ipponi
Martina Cordoni
Elena Bechini
Fabrizia Gentili
Fabio Cosseddu
Antonio D'Arienzo
Lorenzo Andreani
author_sort Edoardo Ipponi
collection DOAJ
description Background: The distal tibia is one of the rarest sites for the onset of malignant and locally aggressive bone tumors. When diagnosed, these lesions should undergo surgical resection with wide margins to eradicate the disease. In the era of limb-sparing surgery, several reconstructive approaches have been proposed and described in modern literature for reconstructing the distal tibia and the ankle. The 3D-printed custom-made prostheses represent an innovative and promising reconstructive option. Several authors highlighted that despite being expensive and prone to some complications such as talar collapse or loosening and soft tissue necrosis, the megaprostheses of the distal tibia could lead to good functional outcomes, also allowing a better range of motion compared to the most common arthrodesis. Materials and methods: We report two cases who suffered from malignant bone tumors localized in the distal tibia and treated with wide resections and the implant of 3D printed custom-made megaprostheses to replace the distal tibia and the ankle. Results: Both patients had excellent functional results (MSTS 30/30) one year after surgery. No local recurrence occurred during the patients’ latest follow-up. Conclusions: Our results support the effectiveness of custom-made implants in replacing the distal tibia and the ankle in orthopedic oncology.
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2029-4174
language English
publishDate 2024-12-01
publisher Vilnius University Press
record_format Article
series Acta Medica Lituanica
spelling doaj-art-1bd1eeb91906410c9f62ac9b970b8cfe2025-02-11T18:08:30ZengVilnius University PressActa Medica Lituanica1392-01382029-41742024-12-0131210.15388/Amed.2024.31.2.13Ankle and Distal Tibia Megaprostheses in Orthopedic Oncology: A Report of Two Cases and Review of the LiteratureEdoardo Ipponi0https://orcid.org/0000-0003-2107-6357Martina Cordoni1https://orcid.org/0009-0005-9353-4320Elena Bechini2https://orcid.org/0009-0004-9276-4362Fabrizia Gentili3Fabio Cosseddu4Antonio D'Arienzo5Lorenzo Andreani6https://orcid.org/0000-0002-8268-6987University of Pisa, Department of Orthopedics and Trauma Surgery, ItalyUniversity of Pisa, Department of Orthopedics and Trauma Surgery, ItalyUniversity of Pisa, Department of Orthopedics and Trauma Surgery, ItalyUniversity of Pisa, Department of Orthopedics and Trauma Surgery, ItalyUniversity of Pisa, Department of Orthopedics and Trauma Surgery, ItalyUniversity of Pisa, Department of Orthopedics and Trauma Surgery, ItalyUniversity of Pisa, Department of Orthopedics and Trauma Surgery, Italy Background: The distal tibia is one of the rarest sites for the onset of malignant and locally aggressive bone tumors. When diagnosed, these lesions should undergo surgical resection with wide margins to eradicate the disease. In the era of limb-sparing surgery, several reconstructive approaches have been proposed and described in modern literature for reconstructing the distal tibia and the ankle. The 3D-printed custom-made prostheses represent an innovative and promising reconstructive option. Several authors highlighted that despite being expensive and prone to some complications such as talar collapse or loosening and soft tissue necrosis, the megaprostheses of the distal tibia could lead to good functional outcomes, also allowing a better range of motion compared to the most common arthrodesis. Materials and methods: We report two cases who suffered from malignant bone tumors localized in the distal tibia and treated with wide resections and the implant of 3D printed custom-made megaprostheses to replace the distal tibia and the ankle. Results: Both patients had excellent functional results (MSTS 30/30) one year after surgery. No local recurrence occurred during the patients’ latest follow-up. Conclusions: Our results support the effectiveness of custom-made implants in replacing the distal tibia and the ankle in orthopedic oncology. https://www.zurnalai.vu.lt/AML/article/view/35827Spindle cell sarcomaAdamantinoma3D printedCustom made prosthesisAdditive manufacturing
spellingShingle Edoardo Ipponi
Martina Cordoni
Elena Bechini
Fabrizia Gentili
Fabio Cosseddu
Antonio D'Arienzo
Lorenzo Andreani
Ankle and Distal Tibia Megaprostheses in Orthopedic Oncology: A Report of Two Cases and Review of the Literature
Acta Medica Lituanica
Spindle cell sarcoma
Adamantinoma
3D printed
Custom made prosthesis
Additive manufacturing
title Ankle and Distal Tibia Megaprostheses in Orthopedic Oncology: A Report of Two Cases and Review of the Literature
title_full Ankle and Distal Tibia Megaprostheses in Orthopedic Oncology: A Report of Two Cases and Review of the Literature
title_fullStr Ankle and Distal Tibia Megaprostheses in Orthopedic Oncology: A Report of Two Cases and Review of the Literature
title_full_unstemmed Ankle and Distal Tibia Megaprostheses in Orthopedic Oncology: A Report of Two Cases and Review of the Literature
title_short Ankle and Distal Tibia Megaprostheses in Orthopedic Oncology: A Report of Two Cases and Review of the Literature
title_sort ankle and distal tibia megaprostheses in orthopedic oncology a report of two cases and review of the literature
topic Spindle cell sarcoma
Adamantinoma
3D printed
Custom made prosthesis
Additive manufacturing
url https://www.zurnalai.vu.lt/AML/article/view/35827
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