Endothelin Level and Its Correlation with Uric Acid in Type 2 Diabetic Multiuse Patients
This research aims to find the direct linkage among the Uric acid rates with Endothelin (ET-1), which is considered the indication of endothelial dysfunction or endothelial damage in patients with T2-DM. This study, included 96 patients with T2-DM and 96 controls, the mean age ranged (56.73 ± 9.14),...
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| Language: | English |
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Mustansiriyah University
2020-08-01
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| Series: | Al-Mustansiriyah Journal of Science |
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| Online Access: | http://mjs.uomustansiriyah.edu.iq/ojs1/index.php/MJS/article/view/849 |
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| author | Zahraa Majid Ismail Zyad Hussein Jawad Ali Jasim Hammood |
| author_facet | Zahraa Majid Ismail Zyad Hussein Jawad Ali Jasim Hammood |
| author_sort | Zahraa Majid Ismail |
| collection | DOAJ |
| description | This research aims to find the direct linkage among the Uric acid rates with Endothelin (ET-1), which is considered the indication of endothelial dysfunction or endothelial damage in patients with T2-DM. This study, included 96 patients with T2-DM and 96 controls, the mean age ranged (56.73 ± 9.14), (56.42 ± 8.74) respectively. Results showed a highly significant increase in Endothelin (ET-1) levels, uric acid, urea, and systolic blood pressure (SBP) was observed as compared with the control group, while Diastolic blood pressure (DBP) and body mass (BMI) were not substantially increased. Additionally, a significant positive correlation was found between ET-1 with uric acid, urea, SBP, DBP in patients with T2-DM (p < 0.05). Finally, elevated uric acid levels in older people who have chronic blood pressure are one of the factors influencing the increased release of ET-1, thus the development of cardiovascular disease. |
| format | Article |
| id | doaj-art-1bcf6d6005384bf890bad4aaef1679da |
| institution | OA Journals |
| issn | 1814-635X 2521-3520 |
| language | English |
| publishDate | 2020-08-01 |
| publisher | Mustansiriyah University |
| record_format | Article |
| series | Al-Mustansiriyah Journal of Science |
| spelling | doaj-art-1bcf6d6005384bf890bad4aaef1679da2025-08-20T02:18:21ZengMustansiriyah UniversityAl-Mustansiriyah Journal of Science1814-635X2521-35202020-08-01313353810.23851/mjs.v31i3.849330Endothelin Level and Its Correlation with Uric Acid in Type 2 Diabetic Multiuse PatientsZahraa Majid Ismail0Zyad Hussein Jawad1Ali Jasim Hammood2Chemistry Department, College of Science, Mustansiriyah University.Chemistry Department, College of Science, Mustansiriyah University.Pharmacy Department, Al-Kut University College.This research aims to find the direct linkage among the Uric acid rates with Endothelin (ET-1), which is considered the indication of endothelial dysfunction or endothelial damage in patients with T2-DM. This study, included 96 patients with T2-DM and 96 controls, the mean age ranged (56.73 ± 9.14), (56.42 ± 8.74) respectively. Results showed a highly significant increase in Endothelin (ET-1) levels, uric acid, urea, and systolic blood pressure (SBP) was observed as compared with the control group, while Diastolic blood pressure (DBP) and body mass (BMI) were not substantially increased. Additionally, a significant positive correlation was found between ET-1 with uric acid, urea, SBP, DBP in patients with T2-DM (p < 0.05). Finally, elevated uric acid levels in older people who have chronic blood pressure are one of the factors influencing the increased release of ET-1, thus the development of cardiovascular disease.http://mjs.uomustansiriyah.edu.iq/ojs1/index.php/MJS/article/view/849endothelin (et-1)hypertension, uric acid. |
| spellingShingle | Zahraa Majid Ismail Zyad Hussein Jawad Ali Jasim Hammood Endothelin Level and Its Correlation with Uric Acid in Type 2 Diabetic Multiuse Patients Al-Mustansiriyah Journal of Science endothelin (et-1) hypertension, uric acid. |
| title | Endothelin Level and Its Correlation with Uric Acid in Type 2 Diabetic Multiuse Patients |
| title_full | Endothelin Level and Its Correlation with Uric Acid in Type 2 Diabetic Multiuse Patients |
| title_fullStr | Endothelin Level and Its Correlation with Uric Acid in Type 2 Diabetic Multiuse Patients |
| title_full_unstemmed | Endothelin Level and Its Correlation with Uric Acid in Type 2 Diabetic Multiuse Patients |
| title_short | Endothelin Level and Its Correlation with Uric Acid in Type 2 Diabetic Multiuse Patients |
| title_sort | endothelin level and its correlation with uric acid in type 2 diabetic multiuse patients |
| topic | endothelin (et-1) hypertension, uric acid. |
| url | http://mjs.uomustansiriyah.edu.iq/ojs1/index.php/MJS/article/view/849 |
| work_keys_str_mv | AT zahraamajidismail endothelinlevelanditscorrelationwithuricacidintype2diabeticmultiusepatients AT zyadhusseinjawad endothelinlevelanditscorrelationwithuricacidintype2diabeticmultiusepatients AT alijasimhammood endothelinlevelanditscorrelationwithuricacidintype2diabeticmultiusepatients |