A closer look: factors impacting HIV durable viral suppression among a cohort of clinic attendees in Trinidad & Tobago
Background In Trinidad and Tobago, high HIV prevalence among key populations necessitates studying factors that impact durable viral suppression (DVS), crucial for effective HIV management and reducing transmission among at-risk networks. This study investigates these factors using clinical data fro...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2025-12-01
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| Series: | HIV Research & Clinical Practice |
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| Online Access: | http://dx.doi.org/10.1080/25787489.2024.2443886 |
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| author | Elena Cyrus Deidre A. Okeke Omari Lavia Mary Jo Trepka Allysha Maragh-Bass Lunthita Duthely Michael Sciauodone Jeffrey Edwards |
| author_facet | Elena Cyrus Deidre A. Okeke Omari Lavia Mary Jo Trepka Allysha Maragh-Bass Lunthita Duthely Michael Sciauodone Jeffrey Edwards |
| author_sort | Elena Cyrus |
| collection | DOAJ |
| description | Background In Trinidad and Tobago, high HIV prevalence among key populations necessitates studying factors that impact durable viral suppression (DVS), crucial for effective HIV management and reducing transmission among at-risk networks. This study investigates these factors using clinical data from a major HIV care clinic in the Caribbean. Methods A retrospective analysis of 533 adult people with HIV (people) at MRFTT from 2017 to 2021 assessed the proportion achieving DVS, defined as a sustained viral load <200 copies/ml over one year. Initial univariate analysis characterized individuals with DVS, followed by bivariate analysis to explore socio-demographic differences. Significant variables from bivariate analysis were examined in a regression model to identify DVS covariates. Results The average age of the sample was 45 years (SD = 10.88), with 52.0% male and 72.1% of African descent. 31.5% achieved durable viral suppression (DVS). Those with DVS were predominantly women (54.1%), older (mean age 45, SD = 11.32), with more frequent clinic visits over five years (mean = 101, SD = 33.26). Regression analysis showed that women (OR = 1.43, 95% CI 0.99–2.07), individuals on long-term antiretroviral therapy (ART) (>5 years) (OR = 1.66, 95% CI 1.03–2.66), and those with extended clinic enrolment (>5 years) (OR = 1.82, 95% CI 1.08–3.06) had higher odds of achieving DVS. Conclusions Only a third of the study sample achieved DVS, with men less likely to reach this goal. Lesser engagement in care correlated with lower DVS rates. Further research into social and structural barriers to clinic attendance, particularly among younger men, is recommended. |
| format | Article |
| id | doaj-art-1bcbaa9e70a74ec69490ce2aea07772d |
| institution | Kabale University |
| issn | 2578-7470 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | HIV Research & Clinical Practice |
| spelling | doaj-art-1bcbaa9e70a74ec69490ce2aea07772d2025-01-20T14:37:59ZengTaylor & Francis GroupHIV Research & Clinical Practice2578-74702025-12-0126110.1080/25787489.2024.24438862443886A closer look: factors impacting HIV durable viral suppression among a cohort of clinic attendees in Trinidad & TobagoElena Cyrus0Deidre A. Okeke1Omari Lavia2Mary Jo Trepka3Allysha Maragh-Bass4Lunthita Duthely5Michael Sciauodone6Jeffrey Edwards7Department of Population Health Sciences, College of Medicine, University of Central FloridaDepartment of Epidemiology, Robert Stempel College of Public Health and Social Work, Florida International UniversityMedical Research Foundation of Trinidad and TobagoDepartment of Epidemiology, Robert Stempel College of Public Health and Social Work, Florida International UniversityGlobal Health and Population ResearchMiller School of Medicine, University of MiamiSchool of Medicine, Tulane UniversityMedical Research Foundation of Trinidad and TobagoBackground In Trinidad and Tobago, high HIV prevalence among key populations necessitates studying factors that impact durable viral suppression (DVS), crucial for effective HIV management and reducing transmission among at-risk networks. This study investigates these factors using clinical data from a major HIV care clinic in the Caribbean. Methods A retrospective analysis of 533 adult people with HIV (people) at MRFTT from 2017 to 2021 assessed the proportion achieving DVS, defined as a sustained viral load <200 copies/ml over one year. Initial univariate analysis characterized individuals with DVS, followed by bivariate analysis to explore socio-demographic differences. Significant variables from bivariate analysis were examined in a regression model to identify DVS covariates. Results The average age of the sample was 45 years (SD = 10.88), with 52.0% male and 72.1% of African descent. 31.5% achieved durable viral suppression (DVS). Those with DVS were predominantly women (54.1%), older (mean age 45, SD = 11.32), with more frequent clinic visits over five years (mean = 101, SD = 33.26). Regression analysis showed that women (OR = 1.43, 95% CI 0.99–2.07), individuals on long-term antiretroviral therapy (ART) (>5 years) (OR = 1.66, 95% CI 1.03–2.66), and those with extended clinic enrolment (>5 years) (OR = 1.82, 95% CI 1.08–3.06) had higher odds of achieving DVS. Conclusions Only a third of the study sample achieved DVS, with men less likely to reach this goal. Lesser engagement in care correlated with lower DVS rates. Further research into social and structural barriers to clinic attendance, particularly among younger men, is recommended.http://dx.doi.org/10.1080/25787489.2024.2443886durable viral suppressionpeople with hivtrinidad and tobagogenderdisparities |
| spellingShingle | Elena Cyrus Deidre A. Okeke Omari Lavia Mary Jo Trepka Allysha Maragh-Bass Lunthita Duthely Michael Sciauodone Jeffrey Edwards A closer look: factors impacting HIV durable viral suppression among a cohort of clinic attendees in Trinidad & Tobago HIV Research & Clinical Practice durable viral suppression people with hiv trinidad and tobago gender disparities |
| title | A closer look: factors impacting HIV durable viral suppression among a cohort of clinic attendees in Trinidad & Tobago |
| title_full | A closer look: factors impacting HIV durable viral suppression among a cohort of clinic attendees in Trinidad & Tobago |
| title_fullStr | A closer look: factors impacting HIV durable viral suppression among a cohort of clinic attendees in Trinidad & Tobago |
| title_full_unstemmed | A closer look: factors impacting HIV durable viral suppression among a cohort of clinic attendees in Trinidad & Tobago |
| title_short | A closer look: factors impacting HIV durable viral suppression among a cohort of clinic attendees in Trinidad & Tobago |
| title_sort | closer look factors impacting hiv durable viral suppression among a cohort of clinic attendees in trinidad tobago |
| topic | durable viral suppression people with hiv trinidad and tobago gender disparities |
| url | http://dx.doi.org/10.1080/25787489.2024.2443886 |
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