CalR and MPL Driver Mutations and Their Role in the Diagnosis and Clinical Course of JAK2-Unmutated Chronic Myeloproliferative Neoplasm: Results from a Pilot Single-Center Study

CalR and MPL Driver Mutations and Their Role in the Diagnosis and Clinical Course of JAK2-Unmutated Chronic Myeloproliferative Neoplasm: Results from a Pilot Single-Center Study

<i>Background and Objectives</i>: Philadelphia (Ph)-negative myeloproliferative neoplasms can exhibit defects in Janus kinase 2 (JAK2), Calreticulin (CalR), and MPL genes. It is possible that the presence of other driver mutations may influence diagnosis and prognosis in patients who do...

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Bibliographic Details
Main Authors: Tarık Onur Tiryaki, Aynur Dağlar Aday, Meliha Nalçacı, Akif Selim Yavuz
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Medicina
Subjects:
myeloproliferative disorders
primary myelofibrosis
essential thrombocythemia
Online Access:https://www.mdpi.com/1648-9144/61/6/962
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