Evidence for Pathogen‐Driven Selection Acting on HLA‐DPB1 in Response to Plasmodium falciparum Malaria in West Africa

Evidence for Pathogen‐Driven Selection Acting on HLA‐DPB1 in Response to Plasmodium falciparum Malaria in West Africa

ABSTRACT African populations remain underrepresented in studies of human genetic diversity, despite a growing interest in understanding how they have adapted to the diverse environments they live in. In particular, understanding the genetic basis of immune adaptation to pathogens is of paramount imp...

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Main Authors: Thomas Goeury, Ndeye Faye, Pascale Gerbault, Viktor Černý, Eric Crubézy, Jacques Chiaroni, Hacene Brouk, Lydie Brunet, Maxime Galan, Natasja G. deGroot, José Manuel Nunes, Alicia Sanchez‐Mazas
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Ecology and Evolution
Subjects:
Africa
HLA
human molecular diversity
malaria
pathogen‐driven selection
plasmodium falciparum
Online Access:https://doi.org/10.1002/ece3.70933
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