Investigating the combined effects of statins and exercise on skeletal muscle mitochondrial content and function, cardiorespiratory fitness and quality of life in individuals with dyslipidaemia: protocol for a randomised placebo-controlled trial

Investigating the combined effects of statins and exercise on skeletal muscle mitochondrial content and function, cardiorespiratory fitness and quality of life in individuals with dyslipidaemia: protocol for a randomised placebo-controlled trial

Introduction Dyslipidaemia, affecting approximately 39% of adults worldwide, is a major risk factor for cardiovascular disease. Individuals with dyslipidaemia are often prescribed statins, which effectively lower plasma low-density lipoprotein cholesterol (LDL-C), thereby reducing the risk of cardio...

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Main Authors: Simon Birk Kjær Jensen, Magni Mohr, Jacob Bejder, Nikolai B Nordsborg, Jacobina Kristiansen, Tórur Sjúrðarson, Jan Rasmussen, Helga Ellingsgaard, Steen Larsen, Sanna á Borg, Jørgen Martin Meinhardsson, Helgi Winther Olsen, Jeppe F Vigh-Larsen
Format: Article
Language:English
Published: BMJ Publishing Group 2025-06-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/6/e101425.full
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