Immune landscape and TAM density in endometrial cancer: implications for immune checkpoint inhibitors efficacy

Immune landscape and TAM density in endometrial cancer: implications for immune checkpoint inhibitors efficacy

Background: Immune checkpoint inhibitors (ICIs) have shown efficacy in endometrial cancer (EC); however, their efficacy varies according to mismatch repair (MMR) status. Notably, even among patients with MMR-deficient (MMRd) or microsatellite instability-high (MSI-H) tumors, approximately one-third...

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Main Authors: Olivia Le Saux, Renaud Sabatier, Isabelle Treilleux, Léa-Isabelle Renaud, Pierre-Emmanuel Brachet, Alejandra Martinez, Jean-Sébastien Frenel, Cyril Abdeddaim, Justine Berthet, Sarah Barrin, Amélie Colombe-Vermorel, Laetitia Odeyer, Alexandra Lainé, Christophe Caux, Bertrand Dubois, Isabelle Ray-Coquard
Format: Article
Language:English
Published: SAGE Publishing 2025-08-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/17588359251347364
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