Research progress on Haemophilus parasuis vaccines
Haemophilus parasuis (HPS) is the causative agent of porcine Glässer’s disease, which has become prevalent in China in recent years. It is characterized by fibrinous polyserositis, arthritis, and meningitis, but often shows mixed infection with other upper respiratory tract pathogens, causing heavy...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Veterinary Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2025.1492144/full |
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| _version_ | 1823858101012398080 |
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| author | Yu Duan Yue Hao Huapeng Feng Jianhong Shu Yulong He |
| author_facet | Yu Duan Yue Hao Huapeng Feng Jianhong Shu Yulong He |
| author_sort | Yu Duan |
| collection | DOAJ |
| description | Haemophilus parasuis (HPS) is the causative agent of porcine Glässer’s disease, which has become prevalent in China in recent years. It is characterized by fibrinous polyserositis, arthritis, and meningitis, but often shows mixed infection with other upper respiratory tract pathogens, causing heavy economic losses to the pig industry. Vaccination is an important means to prevent and control HPS infection, and the currently available vaccines are mainly the inactivated type or subunit vaccines containing immunogenic HPS proteins. This study reviews recent advances in HPS vaccines, analyzes the relative effectiveness of the components of subunit vaccines and discusses the advantages and disadvantages of each vaccine type. The goal is to provide insights for the development of more effective vaccines against Haemophilus parasuis infections in pigs. |
| format | Article |
| id | doaj-art-1b9ec0afcc3d452e9e8caccece4ce18a |
| institution | Kabale University |
| issn | 2297-1769 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj-art-1b9ec0afcc3d452e9e8caccece4ce18a2025-02-11T13:41:01ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692025-02-011210.3389/fvets.2025.14921441492144Research progress on Haemophilus parasuis vaccinesYu DuanYue HaoHuapeng FengJianhong ShuYulong HeHaemophilus parasuis (HPS) is the causative agent of porcine Glässer’s disease, which has become prevalent in China in recent years. It is characterized by fibrinous polyserositis, arthritis, and meningitis, but often shows mixed infection with other upper respiratory tract pathogens, causing heavy economic losses to the pig industry. Vaccination is an important means to prevent and control HPS infection, and the currently available vaccines are mainly the inactivated type or subunit vaccines containing immunogenic HPS proteins. This study reviews recent advances in HPS vaccines, analyzes the relative effectiveness of the components of subunit vaccines and discusses the advantages and disadvantages of each vaccine type. The goal is to provide insights for the development of more effective vaccines against Haemophilus parasuis infections in pigs.https://www.frontiersin.org/articles/10.3389/fvets.2025.1492144/fullHaemophilus parasuisGlässer’s diseasevaccinespathogenesisGlaesserella parasuis |
| spellingShingle | Yu Duan Yue Hao Huapeng Feng Jianhong Shu Yulong He Research progress on Haemophilus parasuis vaccines Frontiers in Veterinary Science Haemophilus parasuis Glässer’s disease vaccines pathogenesis Glaesserella parasuis |
| title | Research progress on Haemophilus parasuis vaccines |
| title_full | Research progress on Haemophilus parasuis vaccines |
| title_fullStr | Research progress on Haemophilus parasuis vaccines |
| title_full_unstemmed | Research progress on Haemophilus parasuis vaccines |
| title_short | Research progress on Haemophilus parasuis vaccines |
| title_sort | research progress on haemophilus parasuis vaccines |
| topic | Haemophilus parasuis Glässer’s disease vaccines pathogenesis Glaesserella parasuis |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2025.1492144/full |
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