Surgical treatment of non-functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderly
Over the past three decades, surgical series of elderly patients treated for pituitary adenomas have been published, all of which used the microscopic transsphenoidal or transcranial approach. The objective of this study was to retrospectively analyze the surgical results of our first 25 elderly pat...
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Thieme Revinter Publicações
2015-09-01
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000900764&lng=en&tlng=en |
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| _version_ | 1849701567733694464 |
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| author | Horacio Armando Marenco Samuel Tau Zymberg Rodrigo de Paula Santos Cláuder Oliveira Ramalho |
| author_facet | Horacio Armando Marenco Samuel Tau Zymberg Rodrigo de Paula Santos Cláuder Oliveira Ramalho |
| author_sort | Horacio Armando Marenco |
| collection | DOAJ |
| description | Over the past three decades, surgical series of elderly patients treated for pituitary adenomas have been published, all of which used the microscopic transsphenoidal or transcranial approach. The objective of this study was to retrospectively analyze the surgical results of our first 25 elderly patients with non-functioning pituitary macroadenoma (NFPM) operated by the endoscopic endonasal approach (EEA). Preoperative visual loss was found in 92.8% of the cases, and 70.8% experienced visual improvement following surgery. Preoperative pituitary dysfunction was found in 69.2% of the cases and postoperative pituitary recovery occurred in 22.2% of them. Mean hospital stay was 6.7 days. The results of this study suggest that surgery remains the first line of treatment for NFPM in the elderly. Because age alone is not a barrier for surgery, patients should be selected for surgical treatment based on their symptoms and clinical condition, as defined by comorbidities. |
| format | Article |
| id | doaj-art-1b99e7d4e3f04a3699ae4d8ffd2201cc |
| institution | DOAJ |
| issn | 1678-4227 |
| language | English |
| publishDate | 2015-09-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-1b99e7d4e3f04a3699ae4d8ffd2201cc2025-08-20T03:17:54ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272015-09-0173976476910.1590/0004-282X20150112S0004-282X2015000900764Surgical treatment of non-functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderlyHoracio Armando MarencoSamuel Tau ZymbergRodrigo de Paula SantosCláuder Oliveira RamalhoOver the past three decades, surgical series of elderly patients treated for pituitary adenomas have been published, all of which used the microscopic transsphenoidal or transcranial approach. The objective of this study was to retrospectively analyze the surgical results of our first 25 elderly patients with non-functioning pituitary macroadenoma (NFPM) operated by the endoscopic endonasal approach (EEA). Preoperative visual loss was found in 92.8% of the cases, and 70.8% experienced visual improvement following surgery. Preoperative pituitary dysfunction was found in 69.2% of the cases and postoperative pituitary recovery occurred in 22.2% of them. Mean hospital stay was 6.7 days. The results of this study suggest that surgery remains the first line of treatment for NFPM in the elderly. Because age alone is not a barrier for surgery, patients should be selected for surgical treatment based on their symptoms and clinical condition, as defined by comorbidities.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000900764&lng=en&tlng=enidososneoplasias hipofisáriasdoenças da hipófiseprocedimentos cirúrgicos endoscópicos |
| spellingShingle | Horacio Armando Marenco Samuel Tau Zymberg Rodrigo de Paula Santos Cláuder Oliveira Ramalho Surgical treatment of non-functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderly Arquivos de Neuro-Psiquiatria idosos neoplasias hipofisárias doenças da hipófise procedimentos cirúrgicos endoscópicos |
| title | Surgical treatment of non-functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderly |
| title_full | Surgical treatment of non-functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderly |
| title_fullStr | Surgical treatment of non-functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderly |
| title_full_unstemmed | Surgical treatment of non-functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderly |
| title_short | Surgical treatment of non-functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderly |
| title_sort | surgical treatment of non functioning pituitary macroadenomas by the endoscopic endonasal approach in the elderly |
| topic | idosos neoplasias hipofisárias doenças da hipófise procedimentos cirúrgicos endoscópicos |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000900764&lng=en&tlng=en |
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