Comparative bioavailability of two oral formulations of clopidogrel: Determination of clopidogrel and its carboxylic acid metabolite (SR26334) under fasting and fed conditions in healthy subjects

Comparative bioavailability of two oral formulations of clopidogrel: Determination of clopidogrel and its carboxylic acid metabolite (SR26334) under fasting and fed conditions in healthy subjects

Two randomized, single dose, 2-period, 2-sequence crossover studies were conducted to evaluate the comparative bioavailability of two clopidogrel formulations under fasting and fed conditions. Assessment of bioequivalence was based upon measurement of plasma concentrations of the parent drug, clopid...

Full description

Saved in:
Bibliographic Details
Main Authors: Brvar Nina, Lachance Sylvain, Lévesque Ann, Breznik Marjanca, Cvitkovič Marčič Lea, Merslavič Mateja, Grabnar Iztok, Mateovič-Rojnik Tatjana
Format: Article
Language:English
Published: Sciendo 2014-03-01
Series:Acta Pharmaceutica
Subjects:
bioavailability
food effect
clopidogrel
clopidogrel carboxylic acid
Online Access:http://www.degruyter.com/view/j/acph.2014.64.issue-1/acph-2014-0001/acph-2014-0001.xml?format=INT
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items