Long-read 16S rRNA amplicon sequencing reveals microbial characteristics in patients with colorectal adenomas and carcinoma lesions in Egypt

Long-read 16S rRNA amplicon sequencing reveals microbial characteristics in patients with colorectal adenomas and carcinoma lesions in Egypt

Abstract Background Colorectal cancer (CRC) is among the five leading causes of cancer incidence and mortality. During the past decade, the role of the gut microbiota and its dysbiosis in colorectal tumorigenesis has been emphasized. Metagenomics and amplicon-based microbiome profiling provided insi...

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Main Authors: Asmaa A. El Leithy, Amira Salah El-Din Youssef, Auhood Nassar, Ramy K. Aziz, Nadin M. Khaled, Mina T. Mahrous, Ghobrial N. Farahat, Aya H. Mohamed, Yasser Mabrouk Bakr
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Gut Pathogens
Subjects:
Microbiome
16S rRNA
Colorectal cancer
Colonic polyps
Online Access:https://doi.org/10.1186/s13099-025-00681-9
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