Succinate Regulates Endothelial Mitochondrial Function and Barrier Integrity
Endothelial dysfunction is a hallmark of several pathological conditions, including cancer, cardiovascular disease and inflammatory disorders. In these conditions, perturbed TCA cycle and subsequent succinate accumulation have been reported. The role of succinate as a regulator of immunological resp...
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| Main Authors: | Reham Atallah, Juergen Gindlhuber, Wolfgang Platzer, Rishi Rajesh, Akos Heinemann |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-12-01
|
| Series: | Antioxidants |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3921/13/12/1579 |
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