ANTITHROMBOTIC THERAPY IN PREVENTION OF CARDIOVASCULAR EVENTS (DEATH, ACUTE MYOCARDIAL INFARCTION, STROKE) IN PATIENTS WITH CHRONIC HEART FAILURE

Chronic heart failure is one of the main clinical challenges of modern medicine. The present paper discusses the features of antithrombotic therapy in prevention of cardiovascular events (death, acute myocardial infarction, stroke) in patients with chronic heart failure. It has been specified, which...

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Main Authors: N.D. Gerasimenko, M.S. Rasin
Format: Article
Language:English
Published: Poltava State Medical University 2017-12-01
Series:Проблеми екології та медицини
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Online Access:https://ecomed-journal.org/index.php/journal/article/view/98
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author N.D. Gerasimenko
M.S. Rasin
author_facet N.D. Gerasimenko
M.S. Rasin
author_sort N.D. Gerasimenko
collection DOAJ
description Chronic heart failure is one of the main clinical challenges of modern medicine. The present paper discusses the features of antithrombotic therapy in prevention of cardiovascular events (death, acute myocardial infarction, stroke) in patients with chronic heart failure. It has been specified, which anticoagulants or antiplatelet agents have advantages taking into account the features of the functioning of organs and systems in patients with heart failure. Antithrombotic therapy is indicated for all patients with atrial fibrillation and heart failure. The feasibility of anticoagulant or antithrombotic therapy has not been proven in patients with sinus rhythm, since the risk of bleeding exceeds the antithrombotic effect in patients of this group. The results of controlled trials recommend anticoagulant therapy for patients with heart failure who are at high risk, particularly in atrial fibrillation, with previous thromboembolic episodes, a significant reduction in the left ventricular ejection fraction, intracardiac thrombosis and in patients with aneurysm. There is also no evidence to prescribe antithrombotic therapy for reducing the risk of stroke and thromboembolism in patients with heart failure and sinus rhythm. The choice of antithrombotic therapy should be guided by the CHA2DS2-VASc and HAS-BLAD indices.
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institution Kabale University
issn 2073-4662
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publishDate 2017-12-01
publisher Poltava State Medical University
record_format Article
series Проблеми екології та медицини
spelling doaj-art-1b7bacc8f1144f9796401ffd79cf3bc22025-08-20T03:54:23ZengPoltava State Medical UniversityПроблеми екології та медицини2073-46622519-23022017-12-01215-6293398ANTITHROMBOTIC THERAPY IN PREVENTION OF CARDIOVASCULAR EVENTS (DEATH, ACUTE MYOCARDIAL INFARCTION, STROKE) IN PATIENTS WITH CHRONIC HEART FAILUREN.D. Gerasimenko0M.S. Rasin1Higher State Educational Establishment of Ukraine «Ukrainian Medical Stomatological Academy», PoltavaHigher State Educational Establishment of Ukraine «Ukrainian Medical Stomatological Academy», PoltavaChronic heart failure is one of the main clinical challenges of modern medicine. The present paper discusses the features of antithrombotic therapy in prevention of cardiovascular events (death, acute myocardial infarction, stroke) in patients with chronic heart failure. It has been specified, which anticoagulants or antiplatelet agents have advantages taking into account the features of the functioning of organs and systems in patients with heart failure. Antithrombotic therapy is indicated for all patients with atrial fibrillation and heart failure. The feasibility of anticoagulant or antithrombotic therapy has not been proven in patients with sinus rhythm, since the risk of bleeding exceeds the antithrombotic effect in patients of this group. The results of controlled trials recommend anticoagulant therapy for patients with heart failure who are at high risk, particularly in atrial fibrillation, with previous thromboembolic episodes, a significant reduction in the left ventricular ejection fraction, intracardiac thrombosis and in patients with aneurysm. There is also no evidence to prescribe antithrombotic therapy for reducing the risk of stroke and thromboembolism in patients with heart failure and sinus rhythm. The choice of antithrombotic therapy should be guided by the CHA2DS2-VASc and HAS-BLAD indices.https://ecomed-journal.org/index.php/journal/article/view/98antithrombotic therapy, prevention of vascular events, chronic heart failure
spellingShingle N.D. Gerasimenko
M.S. Rasin
ANTITHROMBOTIC THERAPY IN PREVENTION OF CARDIOVASCULAR EVENTS (DEATH, ACUTE MYOCARDIAL INFARCTION, STROKE) IN PATIENTS WITH CHRONIC HEART FAILURE
Проблеми екології та медицини
antithrombotic therapy, prevention of vascular events, chronic heart failure
title ANTITHROMBOTIC THERAPY IN PREVENTION OF CARDIOVASCULAR EVENTS (DEATH, ACUTE MYOCARDIAL INFARCTION, STROKE) IN PATIENTS WITH CHRONIC HEART FAILURE
title_full ANTITHROMBOTIC THERAPY IN PREVENTION OF CARDIOVASCULAR EVENTS (DEATH, ACUTE MYOCARDIAL INFARCTION, STROKE) IN PATIENTS WITH CHRONIC HEART FAILURE
title_fullStr ANTITHROMBOTIC THERAPY IN PREVENTION OF CARDIOVASCULAR EVENTS (DEATH, ACUTE MYOCARDIAL INFARCTION, STROKE) IN PATIENTS WITH CHRONIC HEART FAILURE
title_full_unstemmed ANTITHROMBOTIC THERAPY IN PREVENTION OF CARDIOVASCULAR EVENTS (DEATH, ACUTE MYOCARDIAL INFARCTION, STROKE) IN PATIENTS WITH CHRONIC HEART FAILURE
title_short ANTITHROMBOTIC THERAPY IN PREVENTION OF CARDIOVASCULAR EVENTS (DEATH, ACUTE MYOCARDIAL INFARCTION, STROKE) IN PATIENTS WITH CHRONIC HEART FAILURE
title_sort antithrombotic therapy in prevention of cardiovascular events death acute myocardial infarction stroke in patients with chronic heart failure
topic antithrombotic therapy, prevention of vascular events, chronic heart failure
url https://ecomed-journal.org/index.php/journal/article/view/98
work_keys_str_mv AT ndgerasimenko antithrombotictherapyinpreventionofcardiovasculareventsdeathacutemyocardialinfarctionstrokeinpatientswithchronicheartfailure
AT msrasin antithrombotictherapyinpreventionofcardiovasculareventsdeathacutemyocardialinfarctionstrokeinpatientswithchronicheartfailure