Colonic Angiosarcoma Arising in Association with Amyloid Deposits
Angiosarcoma of the colon is rare, as is colonic amyloidosis. To our knowledge, there have been no reported cases of angiosarcoma arising in association with amyloid deposition. Herein, we described a case of 77-year-old man who presented with hematochezia, and a sigmoid mass was found on colonoscop...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2020/3780763 |
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| author | Samar Said Rondell P. Graham Tsung-Teh Wu Saba Yasir Lizhi Zhang Andrew L. Folpe |
| author_facet | Samar Said Rondell P. Graham Tsung-Teh Wu Saba Yasir Lizhi Zhang Andrew L. Folpe |
| author_sort | Samar Said |
| collection | DOAJ |
| description | Angiosarcoma of the colon is rare, as is colonic amyloidosis. To our knowledge, there have been no reported cases of angiosarcoma arising in association with amyloid deposition. Herein, we described a case of 77-year-old man who presented with hematochezia, and a sigmoid mass was found on colonoscopy. Histologic examination of the resected specimen showed extensive nodular deposition of AL-lambda amyloid material in the colonic wall, as well as high-grade angiosarcoma which was closely intermingled with the amyloid deposits. While the occurrence of both colonic amyloidosis and angiosarcoma in this patient may represent pure coincidence, given the intimate association of the angiosarcoma and the amyloid deposition and the rarity of both of these lesions, we hypothesize that angiosarcoma could be secondary to amyloid deposition. |
| format | Article |
| id | doaj-art-1b7acfb323354031bfbf1bf4ef024332 |
| institution | Kabale University |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-1b7acfb323354031bfbf1bf4ef0243322025-02-03T06:06:44ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362020-01-01202010.1155/2020/37807633780763Colonic Angiosarcoma Arising in Association with Amyloid DepositsSamar Said0Rondell P. Graham1Tsung-Teh Wu2Saba Yasir3Lizhi Zhang4Andrew L. Folpe5Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USADepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USADepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USADepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USADepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USADepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USAAngiosarcoma of the colon is rare, as is colonic amyloidosis. To our knowledge, there have been no reported cases of angiosarcoma arising in association with amyloid deposition. Herein, we described a case of 77-year-old man who presented with hematochezia, and a sigmoid mass was found on colonoscopy. Histologic examination of the resected specimen showed extensive nodular deposition of AL-lambda amyloid material in the colonic wall, as well as high-grade angiosarcoma which was closely intermingled with the amyloid deposits. While the occurrence of both colonic amyloidosis and angiosarcoma in this patient may represent pure coincidence, given the intimate association of the angiosarcoma and the amyloid deposition and the rarity of both of these lesions, we hypothesize that angiosarcoma could be secondary to amyloid deposition.http://dx.doi.org/10.1155/2020/3780763 |
| spellingShingle | Samar Said Rondell P. Graham Tsung-Teh Wu Saba Yasir Lizhi Zhang Andrew L. Folpe Colonic Angiosarcoma Arising in Association with Amyloid Deposits Case Reports in Gastrointestinal Medicine |
| title | Colonic Angiosarcoma Arising in Association with Amyloid Deposits |
| title_full | Colonic Angiosarcoma Arising in Association with Amyloid Deposits |
| title_fullStr | Colonic Angiosarcoma Arising in Association with Amyloid Deposits |
| title_full_unstemmed | Colonic Angiosarcoma Arising in Association with Amyloid Deposits |
| title_short | Colonic Angiosarcoma Arising in Association with Amyloid Deposits |
| title_sort | colonic angiosarcoma arising in association with amyloid deposits |
| url | http://dx.doi.org/10.1155/2020/3780763 |
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