Comparative efficacy of sodium oxybate versus placebo on improvement of nighttime sleep in adult patients with narcolepsy: A systematic review and meta-analysis

Comparative efficacy of sodium oxybate versus placebo on improvement of nighttime sleep in adult patients with narcolepsy: A systematic review and meta-analysis

Background: Narcolepsy, a central hypersomnolence disorder, disrupts sleep regulation. Sodium oxybate, a CNS (central nervous system) depressant, is widely used as a treatment, but there are surprisingly very few rigorous studies comparing its effectiveness to placebo in adults. Objectives: To measu...

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Main Authors: Adina Arshad, Muhammad Abdul Muqtadir Qureshi, Muhammad Abdullah Masood, Hafiz Shahbaz Zahoor, Ayesha Nazakat, Anfal Fatima, Javed Iqbal
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:Sleep Medicine: X
Online Access:http://www.sciencedirect.com/science/article/pii/S259014272400034X
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