Successful Long-Term Use of Itraconazole for the Treatment of Aspergillus Diskospondylitis in a Dog
A 5-year-old spayed female German shepherd dog was admitted with a history of generalized stiffness. Neurologic examination revealed mild paraparesis with multifocal spinal pain. Spinal radiographs and magnetic resonance imaging revealed diskospondylitis at L6-7 and multiple sites throughout the tho...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Veterinary Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/907276 |
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| author | Emiko Van Wie Annie V. Chen Stephanie A. Thomovsky Russell L. Tucker |
| author_facet | Emiko Van Wie Annie V. Chen Stephanie A. Thomovsky Russell L. Tucker |
| author_sort | Emiko Van Wie |
| collection | DOAJ |
| description | A 5-year-old spayed female German shepherd dog was admitted with a history of generalized stiffness. Neurologic examination revealed mild paraparesis with multifocal spinal pain. Spinal radiographs and magnetic resonance imaging revealed diskospondylitis at L6-7 and multiple sites throughout the thoracolumbar spine. Biopsy of the intervertebral disk at L6-7 revealed a positive culture for Aspergillus species, and the dog was placed on itraconazole indefinitely. Clinical signs were significantly improved after two weeks of itraconazole. The dog was reevaluated 8 years later for unrelated reasons. No spinal pain was detected. Spinal radiographs revealed a fused L6-7 disk space and collapsed and sclerotic disk spaces at multiple sites. Itraconazole was tolerated by the dog with normal yearly liver enzyme values. To our knowledge, this is the first reported case of successful long-term use of itraconazole for the treatment of Aspergillus diskospondylitis in a dog. |
| format | Article |
| id | doaj-art-1b6c9ce801f44fc28fccfc767c4be73f |
| institution | Kabale University |
| issn | 2090-7001 2090-701X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Veterinary Medicine |
| spelling | doaj-art-1b6c9ce801f44fc28fccfc767c4be73f2025-08-20T03:54:23ZengWileyCase Reports in Veterinary Medicine2090-70012090-701X2013-01-01201310.1155/2013/907276907276Successful Long-Term Use of Itraconazole for the Treatment of Aspergillus Diskospondylitis in a DogEmiko Van Wie0Annie V. Chen1Stephanie A. Thomovsky2Russell L. Tucker3Texas A&M University College of Veterinary Medicine, 422 Raymond Stotzer Parkway, College Station, TX 77843, USAWashington State University College of Veterinary Medicine, P.O. Box 647010, Pullman, WA 99164, USAWashington State University College of Veterinary Medicine, P.O. Box 647010, Pullman, WA 99164, USAWashington State University College of Veterinary Medicine, P.O. Box 647010, Pullman, WA 99164, USAA 5-year-old spayed female German shepherd dog was admitted with a history of generalized stiffness. Neurologic examination revealed mild paraparesis with multifocal spinal pain. Spinal radiographs and magnetic resonance imaging revealed diskospondylitis at L6-7 and multiple sites throughout the thoracolumbar spine. Biopsy of the intervertebral disk at L6-7 revealed a positive culture for Aspergillus species, and the dog was placed on itraconazole indefinitely. Clinical signs were significantly improved after two weeks of itraconazole. The dog was reevaluated 8 years later for unrelated reasons. No spinal pain was detected. Spinal radiographs revealed a fused L6-7 disk space and collapsed and sclerotic disk spaces at multiple sites. Itraconazole was tolerated by the dog with normal yearly liver enzyme values. To our knowledge, this is the first reported case of successful long-term use of itraconazole for the treatment of Aspergillus diskospondylitis in a dog.http://dx.doi.org/10.1155/2013/907276 |
| spellingShingle | Emiko Van Wie Annie V. Chen Stephanie A. Thomovsky Russell L. Tucker Successful Long-Term Use of Itraconazole for the Treatment of Aspergillus Diskospondylitis in a Dog Case Reports in Veterinary Medicine |
| title | Successful Long-Term Use of Itraconazole for the Treatment of Aspergillus Diskospondylitis in a Dog |
| title_full | Successful Long-Term Use of Itraconazole for the Treatment of Aspergillus Diskospondylitis in a Dog |
| title_fullStr | Successful Long-Term Use of Itraconazole for the Treatment of Aspergillus Diskospondylitis in a Dog |
| title_full_unstemmed | Successful Long-Term Use of Itraconazole for the Treatment of Aspergillus Diskospondylitis in a Dog |
| title_short | Successful Long-Term Use of Itraconazole for the Treatment of Aspergillus Diskospondylitis in a Dog |
| title_sort | successful long term use of itraconazole for the treatment of aspergillus diskospondylitis in a dog |
| url | http://dx.doi.org/10.1155/2013/907276 |
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