Assessment of effectiveness of the empiric treatment regimen in tuberculosis patients suspected with multiple drug resistance in the Russian Federation
The article presents the comparative assessment of effectiveness of tuberculosis treatment with empiric chemotherapy regimen IV. The outcomes of treatment with empiric regimen IV of the cases in whom later drug resistance was confirmed were compared with the outcomes of regimen IV prescribed to the...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2018-11-01
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| Series: | Туберкулез и болезни лёгких |
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| Online Access: | https://www.tibl-journal.com/jour/article/view/1191 |
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| author | Sergey A. Sterlikov Anastasiya G. Samoylova Vadim V. Testov Konstantin A. Glebov Irina A. Vasilyeva |
| author_facet | Sergey A. Sterlikov Anastasiya G. Samoylova Vadim V. Testov Konstantin A. Glebov Irina A. Vasilyeva |
| author_sort | Sergey A. Sterlikov |
| collection | DOAJ |
| description | The article presents the comparative assessment of effectiveness of tuberculosis treatment with empiric chemotherapy regimen IV. The outcomes of treatment with empiric regimen IV of the cases in whom later drug resistance was confirmed were compared with the outcomes of regimen IV prescribed to the patients who had confirmed resistance at least to rifampicin. The outcomes of empiric treatment with regimen IV in the cases without confirmed resistance to rifampicin were compared to outcomes of treatment with regimens I, II, and III, prescribed to those sensitive to rifampicin. No statistically significant differences in the number of favorable treatment outcomes were found which allows concluding that it is advisable to prescribe empiric regimen IV if multiple drug resistant tuberculosis is suspected. |
| format | Article |
| id | doaj-art-1b51d7e4e14644c0bc49205bcab2cac3 |
| institution | OA Journals |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| publishDate | 2018-11-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj-art-1b51d7e4e14644c0bc49205bcab2cac32025-08-20T01:47:52ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062018-11-019611283310.21292/2075-1230-2018-96-11-28-331191Assessment of effectiveness of the empiric treatment regimen in tuberculosis patients suspected with multiple drug resistance in the Russian FederationSergey A. Sterlikov0Anastasiya G. Samoylova1Vadim V. Testov2Konstantin A. Glebov3Irina A. Vasilyeva4Central Research Institute for Public Health Organization and InformatizationNational Medical Research Center of Phthisiopulmonology and Infectious DiseasesNational Medical Research Center of Phthisiopulmonology and Infectious DiseasesNational Medical Research Center of Phthisiopulmonology and Infectious DiseasesNational Medical Research Center of Phthisiopulmonology and Infectious DiseasesThe article presents the comparative assessment of effectiveness of tuberculosis treatment with empiric chemotherapy regimen IV. The outcomes of treatment with empiric regimen IV of the cases in whom later drug resistance was confirmed were compared with the outcomes of regimen IV prescribed to the patients who had confirmed resistance at least to rifampicin. The outcomes of empiric treatment with regimen IV in the cases without confirmed resistance to rifampicin were compared to outcomes of treatment with regimens I, II, and III, prescribed to those sensitive to rifampicin. No statistically significant differences in the number of favorable treatment outcomes were found which allows concluding that it is advisable to prescribe empiric regimen IV if multiple drug resistant tuberculosis is suspected.https://www.tibl-journal.com/jour/article/view/1191multiple drug resistant tuberculosistuberculosis treatment outcomestuberculosis chemotherapyempiric treatment |
| spellingShingle | Sergey A. Sterlikov Anastasiya G. Samoylova Vadim V. Testov Konstantin A. Glebov Irina A. Vasilyeva Assessment of effectiveness of the empiric treatment regimen in tuberculosis patients suspected with multiple drug resistance in the Russian Federation Туберкулез и болезни лёгких multiple drug resistant tuberculosis tuberculosis treatment outcomes tuberculosis chemotherapy empiric treatment |
| title | Assessment of effectiveness of the empiric treatment regimen in tuberculosis patients suspected with multiple drug resistance in the Russian Federation |
| title_full | Assessment of effectiveness of the empiric treatment regimen in tuberculosis patients suspected with multiple drug resistance in the Russian Federation |
| title_fullStr | Assessment of effectiveness of the empiric treatment regimen in tuberculosis patients suspected with multiple drug resistance in the Russian Federation |
| title_full_unstemmed | Assessment of effectiveness of the empiric treatment regimen in tuberculosis patients suspected with multiple drug resistance in the Russian Federation |
| title_short | Assessment of effectiveness of the empiric treatment regimen in tuberculosis patients suspected with multiple drug resistance in the Russian Federation |
| title_sort | assessment of effectiveness of the empiric treatment regimen in tuberculosis patients suspected with multiple drug resistance in the russian federation |
| topic | multiple drug resistant tuberculosis tuberculosis treatment outcomes tuberculosis chemotherapy empiric treatment |
| url | https://www.tibl-journal.com/jour/article/view/1191 |
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