Underestimated reason of hyperkalemia in diabetic patients: type IV renal tubular acidosis- mini review

Diabetes mellitus is chronic disease with increasing prevalence, and may cause many organ complications, including kidneys. Reduced creatinine clearance and kidney failure are important, but hyperkalemia may be present in diabetic patients even before these problems. There may be many reasons of hyp...

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Main Authors: Sibel Ertek, Kayser Caglar
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Clinical Diabetes and Healthcare
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcdhc.2025.1570868/full
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author Sibel Ertek
Kayser Caglar
author_facet Sibel Ertek
Kayser Caglar
author_sort Sibel Ertek
collection DOAJ
description Diabetes mellitus is chronic disease with increasing prevalence, and may cause many organ complications, including kidneys. Reduced creatinine clearance and kidney failure are important, but hyperkalemia may be present in diabetic patients even before these problems. There may be many reasons of hyperkalemia in this group of patients. Type IV renal tubular acidosis is important cause of generally mild hyperkalemia, and it is a treatable condition. ‘‘Polypharmacy’’ –which is very common in diabetic patients due to accompanying other diseases- may trigger electrolyte imbalance. Underlying causes should be investigated and treatment should be done before it worsens.
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spelling doaj-art-1b4ea702bed54d74bc0080f396e380f52025-08-20T03:28:43ZengFrontiers Media S.A.Frontiers in Clinical Diabetes and Healthcare2673-66162025-07-01610.3389/fcdhc.2025.15708681570868Underestimated reason of hyperkalemia in diabetic patients: type IV renal tubular acidosis- mini reviewSibel Ertek0Kayser Caglar1Endocrinology and Metabolic Diseases Department, Losante Hospital, Ankara, TürkiyeNephrology Department, Losante Hospital, Ankara, TürkiyeDiabetes mellitus is chronic disease with increasing prevalence, and may cause many organ complications, including kidneys. Reduced creatinine clearance and kidney failure are important, but hyperkalemia may be present in diabetic patients even before these problems. There may be many reasons of hyperkalemia in this group of patients. Type IV renal tubular acidosis is important cause of generally mild hyperkalemia, and it is a treatable condition. ‘‘Polypharmacy’’ –which is very common in diabetic patients due to accompanying other diseases- may trigger electrolyte imbalance. Underlying causes should be investigated and treatment should be done before it worsens.https://www.frontiersin.org/articles/10.3389/fcdhc.2025.1570868/fulldiabeteshyperkalemiatype IV renal tubular acidosishyporeninemic hypoaldosteronismpotassium
spellingShingle Sibel Ertek
Kayser Caglar
Underestimated reason of hyperkalemia in diabetic patients: type IV renal tubular acidosis- mini review
Frontiers in Clinical Diabetes and Healthcare
diabetes
hyperkalemia
type IV renal tubular acidosis
hyporeninemic hypoaldosteronism
potassium
title Underestimated reason of hyperkalemia in diabetic patients: type IV renal tubular acidosis- mini review
title_full Underestimated reason of hyperkalemia in diabetic patients: type IV renal tubular acidosis- mini review
title_fullStr Underestimated reason of hyperkalemia in diabetic patients: type IV renal tubular acidosis- mini review
title_full_unstemmed Underestimated reason of hyperkalemia in diabetic patients: type IV renal tubular acidosis- mini review
title_short Underestimated reason of hyperkalemia in diabetic patients: type IV renal tubular acidosis- mini review
title_sort underestimated reason of hyperkalemia in diabetic patients type iv renal tubular acidosis mini review
topic diabetes
hyperkalemia
type IV renal tubular acidosis
hyporeninemic hypoaldosteronism
potassium
url https://www.frontiersin.org/articles/10.3389/fcdhc.2025.1570868/full
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