Gametogenesis in malaria parasites is mediated by the cGMP-dependent protein kinase.
Malaria parasite transmission requires differentiation of male and female gametocytes into gametes within a mosquito following a blood meal. A mosquito-derived molecule, xanthurenic acid (XA), can trigger gametogenesis, but the signalling events controlling this process in the human malaria parasite...
Saved in:
| Main Authors: | Louisa McRobert, Cathy J Taylor, Wensheng Deng, Quinton L Fivelman, Ross M Cummings, Spencer D Polley, Oliver Billker, David A Baker |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-06-01
|
| Series: | PLoS Biology |
| Online Access: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.0060139&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Phosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca²⁺ signals at key decision points in the life cycle of malaria parasites.
by: Mathieu Brochet, et al.
Published: (2014-03-01) -
Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites.
by: Konstantinos Koussis, et al.
Published: (2024-06-01) -
Spatiotemporal and functional characterisation of the Plasmodium falciparum cGMP-dependent protein kinase.
by: Christine S Hopp, et al.
Published: (2012-01-01) -
Crystal structures of the carboxyl cGMP binding domain of the Plasmodium falciparum cGMP-dependent protein kinase reveal a novel capping triad crucial for merozoite egress.
by: Jeong Joo Kim, et al.
Published: (2015-02-01) -
Nitric oxide releasing nanofiber stimulates revascularization in response to ischemia via cGMP-dependent protein kinase.
by: Kyung Hye Lee, et al.
Published: (2024-01-01)