From the pathogenesis of chronic cerebral ischemia to targeted therapy
Chronic progressive cerebrovascular pathology is a powerful disabling factor in modern society. Chronic cerebral ischemia is based on microcirculation and neuroinflammation problems, which are mutually potentiating pathogenetic aspects. As a search for modern pathogenetically oriented targeted thera...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation
2024-12-01
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| Series: | Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева |
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| Online Access: | https://www.bekhterevreview.com/jour/article/view/1071 |
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| _version_ | 1849388982346973184 |
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| author | D. V. Zakharov Yu. V. Yarygina V. A. Mikhailov |
| author_facet | D. V. Zakharov Yu. V. Yarygina V. A. Mikhailov |
| author_sort | D. V. Zakharov |
| collection | DOAJ |
| description | Chronic progressive cerebrovascular pathology is a powerful disabling factor in modern society. Chronic cerebral ischemia is based on microcirculation and neuroinflammation problems, which are mutually potentiating pathogenetic aspects. As a search for modern pathogenetically oriented targeted therapy, great attention is paid to cerebral capillary disease, oxidative stress in brain tissue and the issues of suppressing neuroinflammation. The article presents the materials of experimental and clinical studies of Ginkgo biloba extract and choline, as well as their combination — Choline Strong® |
| format | Article |
| id | doaj-art-1b40be9963be40f8bf6c675aee41b39d |
| institution | Kabale University |
| issn | 2313-7053 2713-055X |
| language | Russian |
| publishDate | 2024-12-01 |
| publisher | Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation |
| record_format | Article |
| series | Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева |
| spelling | doaj-art-1b40be9963be40f8bf6c675aee41b39d2025-08-20T03:42:06ZrusFederal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian FederationОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева2313-70532713-055X2024-12-01584-112212810.31363/2313-7053-2024-1060574From the pathogenesis of chronic cerebral ischemia to targeted therapyD. V. Zakharov0Yu. V. Yarygina1V. A. Mikhailov2V.M. Bekhterev National MedicalResearchCenterfor Psychiatry and NeurologyV.M. Bekhterev National MedicalResearchCenterfor Psychiatry and NeurologyV.M. Bekhterev National MedicalResearchCenterfor Psychiatry and NeurologyChronic progressive cerebrovascular pathology is a powerful disabling factor in modern society. Chronic cerebral ischemia is based on microcirculation and neuroinflammation problems, which are mutually potentiating pathogenetic aspects. As a search for modern pathogenetically oriented targeted therapy, great attention is paid to cerebral capillary disease, oxidative stress in brain tissue and the issues of suppressing neuroinflammation. The article presents the materials of experimental and clinical studies of Ginkgo biloba extract and choline, as well as their combination — Choline Strong®https://www.bekhterevreview.com/jour/article/view/1071microangiopathycognitive dysfunctionneuroinflammationoxidative stressginkgo bilobaacetylcholinecholine strong |
| spellingShingle | D. V. Zakharov Yu. V. Yarygina V. A. Mikhailov From the pathogenesis of chronic cerebral ischemia to targeted therapy Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева microangiopathy cognitive dysfunction neuroinflammation oxidative stress ginkgo biloba acetylcholine choline strong |
| title | From the pathogenesis of chronic cerebral ischemia to targeted therapy |
| title_full | From the pathogenesis of chronic cerebral ischemia to targeted therapy |
| title_fullStr | From the pathogenesis of chronic cerebral ischemia to targeted therapy |
| title_full_unstemmed | From the pathogenesis of chronic cerebral ischemia to targeted therapy |
| title_short | From the pathogenesis of chronic cerebral ischemia to targeted therapy |
| title_sort | from the pathogenesis of chronic cerebral ischemia to targeted therapy |
| topic | microangiopathy cognitive dysfunction neuroinflammation oxidative stress ginkgo biloba acetylcholine choline strong |
| url | https://www.bekhterevreview.com/jour/article/view/1071 |
| work_keys_str_mv | AT dvzakharov fromthepathogenesisofchroniccerebralischemiatotargetedtherapy AT yuvyarygina fromthepathogenesisofchroniccerebralischemiatotargetedtherapy AT vamikhailov fromthepathogenesisofchroniccerebralischemiatotargetedtherapy |