The COVID-19 Prevalence among Children: Hypotheses for Low Infection Rate and Few Severe Forms among This Age Group in Sub-Saharan Africa
Despite some cases of severe or critical manifestations of the coronavirus disease 2019 (COVID-19) described among children, the prevalence of this infection in the pediatric population is quite low worldwide, particularly in sub-Saharan Africa. Current data suggest indeed that, independent of the p...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Interdisciplinary Perspectives on Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2021/4258414 |
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| author | Sylvain Raoul Simeni Njonnou Nadia Christelle Noumedem Anangmo Fernando Kemta Lekpa Diomede Noukeu Njinkui Dominique Enyama Christian Ngongang Ouankou Eric Vounsia Balti Esther Astrid Mbono Samba Eloumba Jean Roger Moulion Tapouh Simeon Pierre Choukem |
| author_facet | Sylvain Raoul Simeni Njonnou Nadia Christelle Noumedem Anangmo Fernando Kemta Lekpa Diomede Noukeu Njinkui Dominique Enyama Christian Ngongang Ouankou Eric Vounsia Balti Esther Astrid Mbono Samba Eloumba Jean Roger Moulion Tapouh Simeon Pierre Choukem |
| author_sort | Sylvain Raoul Simeni Njonnou |
| collection | DOAJ |
| description | Despite some cases of severe or critical manifestations of the coronavirus disease 2019 (COVID-19) described among children, the prevalence of this infection in the pediatric population is quite low worldwide, particularly in sub-Saharan Africa. Current data suggest indeed that, independent of the population considered overall, severe and critical cases of COVID-19 are rare among children. This observation prompted us to discuss the possible hypotheses which could explain the low prevalence of COVID-19 among children; amongst others, we discuss (1) immunomodulation by the Bacillus Calmette–Guerin vaccine or by some parasitic infections such as malaria, schistosomiasis, and helminthiasis and (2) cross immunization with other coronaviruses commonly found in the sub-Saharan African setting. |
| format | Article |
| id | doaj-art-1b34c74db0dd42ea89e92e49185e01e3 |
| institution | OA Journals |
| issn | 1687-708X 1687-7098 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Interdisciplinary Perspectives on Infectious Diseases |
| spelling | doaj-art-1b34c74db0dd42ea89e92e49185e01e32025-08-20T02:02:20ZengWileyInterdisciplinary Perspectives on Infectious Diseases1687-708X1687-70982021-01-01202110.1155/2021/42584144258414The COVID-19 Prevalence among Children: Hypotheses for Low Infection Rate and Few Severe Forms among This Age Group in Sub-Saharan AfricaSylvain Raoul Simeni Njonnou0Nadia Christelle Noumedem Anangmo1Fernando Kemta Lekpa2Diomede Noukeu Njinkui3Dominique Enyama4Christian Ngongang Ouankou5Eric Vounsia Balti6Esther Astrid Mbono Samba Eloumba7Jean Roger Moulion Tapouh8Simeon Pierre Choukem9Department of Internal Medicine and Specialties, Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, CameroonDepartment of Microbiology, Haematology and Immunology, Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, CameroonDepartment of Internal Medicine and Specialties, Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, CameroonThe University of Dschang Taskforce for the Elimination of COVID-19 (UNITED#COVID-19), Dschang, CameroonThe University of Dschang Taskforce for the Elimination of COVID-19 (UNITED#COVID-19), Dschang, CameroonDepartment of Internal Medicine and Specialties, Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, CameroonDepartment of Internal Medicine and Specialties, Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, CameroonEndocrine and Diabetes Unit and National Obesity Centre, Department of Internal Medicine, Yaounde Central Hospital, Yaounde, CameroonThe University of Dschang Taskforce for the Elimination of COVID-19 (UNITED#COVID-19), Dschang, CameroonDepartment of Internal Medicine and Specialties, Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, CameroonDespite some cases of severe or critical manifestations of the coronavirus disease 2019 (COVID-19) described among children, the prevalence of this infection in the pediatric population is quite low worldwide, particularly in sub-Saharan Africa. Current data suggest indeed that, independent of the population considered overall, severe and critical cases of COVID-19 are rare among children. This observation prompted us to discuss the possible hypotheses which could explain the low prevalence of COVID-19 among children; amongst others, we discuss (1) immunomodulation by the Bacillus Calmette–Guerin vaccine or by some parasitic infections such as malaria, schistosomiasis, and helminthiasis and (2) cross immunization with other coronaviruses commonly found in the sub-Saharan African setting.http://dx.doi.org/10.1155/2021/4258414 |
| spellingShingle | Sylvain Raoul Simeni Njonnou Nadia Christelle Noumedem Anangmo Fernando Kemta Lekpa Diomede Noukeu Njinkui Dominique Enyama Christian Ngongang Ouankou Eric Vounsia Balti Esther Astrid Mbono Samba Eloumba Jean Roger Moulion Tapouh Simeon Pierre Choukem The COVID-19 Prevalence among Children: Hypotheses for Low Infection Rate and Few Severe Forms among This Age Group in Sub-Saharan Africa Interdisciplinary Perspectives on Infectious Diseases |
| title | The COVID-19 Prevalence among Children: Hypotheses for Low Infection Rate and Few Severe Forms among This Age Group in Sub-Saharan Africa |
| title_full | The COVID-19 Prevalence among Children: Hypotheses for Low Infection Rate and Few Severe Forms among This Age Group in Sub-Saharan Africa |
| title_fullStr | The COVID-19 Prevalence among Children: Hypotheses for Low Infection Rate and Few Severe Forms among This Age Group in Sub-Saharan Africa |
| title_full_unstemmed | The COVID-19 Prevalence among Children: Hypotheses for Low Infection Rate and Few Severe Forms among This Age Group in Sub-Saharan Africa |
| title_short | The COVID-19 Prevalence among Children: Hypotheses for Low Infection Rate and Few Severe Forms among This Age Group in Sub-Saharan Africa |
| title_sort | covid 19 prevalence among children hypotheses for low infection rate and few severe forms among this age group in sub saharan africa |
| url | http://dx.doi.org/10.1155/2021/4258414 |
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