Potent broadly neutralizing antibodies mediate efficient antibody-dependent phagocytosis of HIV-infected cells.

Potent broadly neutralizing antibodies mediate efficient antibody-dependent phagocytosis of HIV-infected cells.

Antibody-dependent cellular phagocytosis (ADCP) has been implicated in protection against HIV-1. However, methods for measuring ADCP currently rely on the phagocytosis of gp120- or gp41-coated beads that do not reflect physiologically relevant conformations of the viral envelope glycoprotein or the...

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Bibliographic Details
Main Authors: Brian J Snow, Nida K Keles, Michael W Grunst, Sanath Kumar Janaka, Ryan T Behrens, David T Evans
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012665
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