A structure-based in silico analysis of the Kell blood group system

A structure-based in silico analysis of the Kell blood group system

Kell is one of the most complex blood group systems, with a highly polymorphic genetic background. Extensive allelic variations in the KEL gene affect the encoded erythrocyte surface protein Kell. Genetic variants causing aberrant splicing, premature termination of protein translation, or specific a...

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Bibliographic Details
Main Authors:	Gabriele Mayr, Maike Bublitz, Tim A. Steiert, Britt-Sabina Löscher, Michael Wittig, Hesham ElAbd, Christoph Gassner, Andre Franke
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-12-01
Series:	Frontiers in Immunology
Subjects:	Kell blood group system protein structural modeling KEL missense variants antigens protein variants analysis phenotype
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1452637/full
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