Global, Regional, and National Burden of Nonrheumatic Valvular Heart Disease and Its Attributable Risk Factors in 204 Countries and Territories, 1990 to 2019: Results From the Global Burden of Disease Study 2019
Background Nonrheumatic valvular heart disease (NRVD) is increasingly becoming a significant public health concern, particularly among older people. In the context of population aging, a detailed report on the epidemiological trends of NRVD is crucial for policymakers to effectively allocate health...
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Wiley
2024-11-01
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| Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
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| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.124.034459 |
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| author | Le Li Limin Liu Zhicheng Hu Likun Zhou Zhuxin Zhang Lingmin Wu Ligang Ding Zhao Hu Lihui Zheng Yan Yao |
| author_facet | Le Li Limin Liu Zhicheng Hu Likun Zhou Zhuxin Zhang Lingmin Wu Ligang Ding Zhao Hu Lihui Zheng Yan Yao |
| author_sort | Le Li |
| collection | DOAJ |
| description | Background Nonrheumatic valvular heart disease (NRVD) is increasingly becoming a significant public health concern, particularly among older people. In the context of population aging, a detailed report on the epidemiological trends of NRVD is crucial for policymakers to effectively allocate health care resources. This study aimed to explore these trends using data from the GBD (Global Burden of Disease) 2019 study. Methods and Results We assessed the changing trends of the incidence, mortality, and disability‐adjusted life years rates for NRVD by calculating the estimated annual percentage change for each. Additionally, we examined the impact of a region's level of social development on NRVD epidemiological trends and identified key risk factors contributing to NRVD‐related deaths. Between 1990 and 2019, the global incidence of NRVD showed a gradual increase, with an estimated annual percentage change of 0.39 (95% CI, 0.30–0.48). The data revealed that women and older people are more likely to develop NRVD. High‐sociodemographic index countries exhibited higher age‐standardized incidence and mortality rates compared with low‐ and middle‐sociodemographic index countries. The most significant risk factor for NRVD‐related mortality was identified as high systolic blood pressure. Conclusions Over the past 3 decades, the burden of NRVD has intensified, indicating a need for more health care resources to address this issue, which is closely associated with an aging population. Currently, high‐sociodemographic index countries report the highest incidences and deaths due to NRVD. However, low‐ and middle‐sociodemographic index countries should also implement measures to manage the rapidly increasing burden of NRVD. |
| format | Article |
| id | doaj-art-1b1844d170ce4b6d9cceb385c467a3cc |
| institution | OA Journals |
| issn | 2047-9980 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| spelling | doaj-art-1b1844d170ce4b6d9cceb385c467a3cc2025-08-20T02:07:28ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802024-11-01132110.1161/JAHA.124.034459Global, Regional, and National Burden of Nonrheumatic Valvular Heart Disease and Its Attributable Risk Factors in 204 Countries and Territories, 1990 to 2019: Results From the Global Burden of Disease Study 2019Le Li0Limin Liu1Zhicheng Hu2Likun Zhou3Zhuxin Zhang4Lingmin Wu5Ligang Ding6Zhao Hu7Lihui Zheng8Yan Yao9Arrhythmia Center, Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College National Center for Cardiovascular Diseases, Fuwai Hospital Beijing ChinaArrhythmia Center, Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College National Center for Cardiovascular Diseases, Fuwai Hospital Beijing ChinaArrhythmia Center, Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College National Center for Cardiovascular Diseases, Fuwai Hospital Beijing ChinaArrhythmia Center, Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College National Center for Cardiovascular Diseases, Fuwai Hospital Beijing ChinaArrhythmia Center, Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College National Center for Cardiovascular Diseases, Fuwai Hospital Beijing ChinaArrhythmia Center, Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College National Center for Cardiovascular Diseases, Fuwai Hospital Beijing ChinaArrhythmia Center, Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College National Center for Cardiovascular Diseases, Fuwai Hospital Beijing ChinaArrhythmia Center, Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College National Center for Cardiovascular Diseases, Fuwai Hospital Beijing ChinaArrhythmia Center, Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College National Center for Cardiovascular Diseases, Fuwai Hospital Beijing ChinaArrhythmia Center, Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College National Center for Cardiovascular Diseases, Fuwai Hospital Beijing ChinaBackground Nonrheumatic valvular heart disease (NRVD) is increasingly becoming a significant public health concern, particularly among older people. In the context of population aging, a detailed report on the epidemiological trends of NRVD is crucial for policymakers to effectively allocate health care resources. This study aimed to explore these trends using data from the GBD (Global Burden of Disease) 2019 study. Methods and Results We assessed the changing trends of the incidence, mortality, and disability‐adjusted life years rates for NRVD by calculating the estimated annual percentage change for each. Additionally, we examined the impact of a region's level of social development on NRVD epidemiological trends and identified key risk factors contributing to NRVD‐related deaths. Between 1990 and 2019, the global incidence of NRVD showed a gradual increase, with an estimated annual percentage change of 0.39 (95% CI, 0.30–0.48). The data revealed that women and older people are more likely to develop NRVD. High‐sociodemographic index countries exhibited higher age‐standardized incidence and mortality rates compared with low‐ and middle‐sociodemographic index countries. The most significant risk factor for NRVD‐related mortality was identified as high systolic blood pressure. Conclusions Over the past 3 decades, the burden of NRVD has intensified, indicating a need for more health care resources to address this issue, which is closely associated with an aging population. Currently, high‐sociodemographic index countries report the highest incidences and deaths due to NRVD. However, low‐ and middle‐sociodemographic index countries should also implement measures to manage the rapidly increasing burden of NRVD.https://www.ahajournals.org/doi/10.1161/JAHA.124.034459Global Burden of Diseasenonrheumatic valvular heart diseasepopulation agingsociodemographic index |
| spellingShingle | Le Li Limin Liu Zhicheng Hu Likun Zhou Zhuxin Zhang Lingmin Wu Ligang Ding Zhao Hu Lihui Zheng Yan Yao Global, Regional, and National Burden of Nonrheumatic Valvular Heart Disease and Its Attributable Risk Factors in 204 Countries and Territories, 1990 to 2019: Results From the Global Burden of Disease Study 2019 Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease Global Burden of Disease nonrheumatic valvular heart disease population aging sociodemographic index |
| title | Global, Regional, and National Burden of Nonrheumatic Valvular Heart Disease and Its Attributable Risk Factors in 204 Countries and Territories, 1990 to 2019: Results From the Global Burden of Disease Study 2019 |
| title_full | Global, Regional, and National Burden of Nonrheumatic Valvular Heart Disease and Its Attributable Risk Factors in 204 Countries and Territories, 1990 to 2019: Results From the Global Burden of Disease Study 2019 |
| title_fullStr | Global, Regional, and National Burden of Nonrheumatic Valvular Heart Disease and Its Attributable Risk Factors in 204 Countries and Territories, 1990 to 2019: Results From the Global Burden of Disease Study 2019 |
| title_full_unstemmed | Global, Regional, and National Burden of Nonrheumatic Valvular Heart Disease and Its Attributable Risk Factors in 204 Countries and Territories, 1990 to 2019: Results From the Global Burden of Disease Study 2019 |
| title_short | Global, Regional, and National Burden of Nonrheumatic Valvular Heart Disease and Its Attributable Risk Factors in 204 Countries and Territories, 1990 to 2019: Results From the Global Burden of Disease Study 2019 |
| title_sort | global regional and national burden of nonrheumatic valvular heart disease and its attributable risk factors in 204 countries and territories 1990 to 2019 results from the global burden of disease study 2019 |
| topic | Global Burden of Disease nonrheumatic valvular heart disease population aging sociodemographic index |
| url | https://www.ahajournals.org/doi/10.1161/JAHA.124.034459 |
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