Impact of elevated CO2 level and egg quiescence duration on gene expression in the peripheral olfactory system of Aedes aegypti
Abstract Elevation in CO2 can significantly impact the biology of various organisms, affecting life-history traits of both aquatic and terrestrial forms, including disease-vectoring mosquitoes. For mosquitoes, this effect is accentuated by egg quiescence duration, resulting in a change in foraging o...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-04-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-025-98159-w |
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| author | Sukritha Nalikkaramal Sharon Rose Hill Rickard Ignell |
| author_facet | Sukritha Nalikkaramal Sharon Rose Hill Rickard Ignell |
| author_sort | Sukritha Nalikkaramal |
| collection | DOAJ |
| description | Abstract Elevation in CO2 can significantly impact the biology of various organisms, affecting life-history traits of both aquatic and terrestrial forms, including disease-vectoring mosquitoes. For mosquitoes, this effect is accentuated by egg quiescence duration, resulting in a change in foraging of adult females. Female mosquitoes rely on their olfactory system for locating resources, such as nectar and blood. This study employs a transcriptomic approach to investigate how a projected elevation in CO2 level, under a worst-case scenario, interacts with extended egg quiescence duration to modulate the molecular machinery of the peripheral olfactory system, the antennae and maxillary palps, of the yellow fever mosquito, Aedes aegypti. The transcriptome analysis demonstrates significant changes in the abundance of genes related to metabolism, xenobiotics degradation and chemosensory function, with the most pronounced effects observed in the CO2 sensing tissue, the maxillary palp. The study provides novel insights into how anthropogenic climate change can modulate the olfactory sensory system of disease vectors, which may have cascading effects on resource-seeking behaviour. |
| format | Article |
| id | doaj-art-1b12e7ea58454d75a0c9177deb10b0bf |
| institution | DOAJ |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-1b12e7ea58454d75a0c9177deb10b0bf2025-08-20T03:13:54ZengNature PortfolioScientific Reports2045-23222025-04-0115111110.1038/s41598-025-98159-wImpact of elevated CO2 level and egg quiescence duration on gene expression in the peripheral olfactory system of Aedes aegyptiSukritha Nalikkaramal0Sharon Rose Hill1Rickard Ignell2Department of Plant Protection Biology, Disease Vector GroupDepartment of Plant Protection Biology, Disease Vector GroupDepartment of Plant Protection Biology, Disease Vector GroupAbstract Elevation in CO2 can significantly impact the biology of various organisms, affecting life-history traits of both aquatic and terrestrial forms, including disease-vectoring mosquitoes. For mosquitoes, this effect is accentuated by egg quiescence duration, resulting in a change in foraging of adult females. Female mosquitoes rely on their olfactory system for locating resources, such as nectar and blood. This study employs a transcriptomic approach to investigate how a projected elevation in CO2 level, under a worst-case scenario, interacts with extended egg quiescence duration to modulate the molecular machinery of the peripheral olfactory system, the antennae and maxillary palps, of the yellow fever mosquito, Aedes aegypti. The transcriptome analysis demonstrates significant changes in the abundance of genes related to metabolism, xenobiotics degradation and chemosensory function, with the most pronounced effects observed in the CO2 sensing tissue, the maxillary palp. The study provides novel insights into how anthropogenic climate change can modulate the olfactory sensory system of disease vectors, which may have cascading effects on resource-seeking behaviour.https://doi.org/10.1038/s41598-025-98159-wMosquitoesCarbon dioxideClimate changeEgg quiescenceOlfactory systemTranscriptome |
| spellingShingle | Sukritha Nalikkaramal Sharon Rose Hill Rickard Ignell Impact of elevated CO2 level and egg quiescence duration on gene expression in the peripheral olfactory system of Aedes aegypti Scientific Reports Mosquitoes Carbon dioxide Climate change Egg quiescence Olfactory system Transcriptome |
| title | Impact of elevated CO2 level and egg quiescence duration on gene expression in the peripheral olfactory system of Aedes aegypti |
| title_full | Impact of elevated CO2 level and egg quiescence duration on gene expression in the peripheral olfactory system of Aedes aegypti |
| title_fullStr | Impact of elevated CO2 level and egg quiescence duration on gene expression in the peripheral olfactory system of Aedes aegypti |
| title_full_unstemmed | Impact of elevated CO2 level and egg quiescence duration on gene expression in the peripheral olfactory system of Aedes aegypti |
| title_short | Impact of elevated CO2 level and egg quiescence duration on gene expression in the peripheral olfactory system of Aedes aegypti |
| title_sort | impact of elevated co2 level and egg quiescence duration on gene expression in the peripheral olfactory system of aedes aegypti |
| topic | Mosquitoes Carbon dioxide Climate change Egg quiescence Olfactory system Transcriptome |
| url | https://doi.org/10.1038/s41598-025-98159-w |
| work_keys_str_mv | AT sukrithanalikkaramal impactofelevatedco2levelandeggquiescencedurationongeneexpressionintheperipheralolfactorysystemofaedesaegypti AT sharonrosehill impactofelevatedco2levelandeggquiescencedurationongeneexpressionintheperipheralolfactorysystemofaedesaegypti AT rickardignell impactofelevatedco2levelandeggquiescencedurationongeneexpressionintheperipheralolfactorysystemofaedesaegypti |