Burden of cancer attributable to sedentary behaviour in Germany: an epidemiological analysis of survey data
Objectives Sedentary behaviour (SB) is associated with increased risks of breast, colorectal, endometrial, ovarian and rectal cancers. However, the number of cancer cases attributable to SB in Germany and the associated costs are unknown.Setting Numbers and proportions (population-attributable fract...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2025-01-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/15/1/e094304.full |
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| author | Michael Leitzmann Wilm Quentin Katharina Schaber Tobias Pukrop Michael J Stein Carmen Jochem |
| author_facet | Michael Leitzmann Wilm Quentin Katharina Schaber Tobias Pukrop Michael J Stein Carmen Jochem |
| author_sort | Michael Leitzmann |
| collection | DOAJ |
| description | Objectives Sedentary behaviour (SB) is associated with increased risks of breast, colorectal, endometrial, ovarian and rectal cancers. However, the number of cancer cases attributable to SB in Germany and the associated costs are unknown.Setting Numbers and proportions (population-attributable fractions, PAF) of new cancer cases attributable to SB with published risk estimates for Germany for the years 2024, 2030 and 2040.Participants Sex-specific and age-specific population projections, national cancer incidence and exposure data. Primary and secondary outcome measures: new cancer cases attributable to SB and healthcare costs associated with cancer cases attributable to SB in Germany for the year 2024.Results Estimated numbers of cancers attributable to SB are projected to be up to 7612 cases (6% of total cancer cases) in 2024, up to 7899 cases (6%) in 2030 and up to 8245 cases (6%) in 2040. The PAF attributable to SB in women is 3% for breast cancer, 8% for colon cancer, 9% for both endometrial and ovarian cancers and 2% for rectal cancer. In men, the PAF is 9% for colon cancer and 3% for rectal cancer. In 2024, the estimated costs of SB-attributable cancers are €270 million for colon cancer, €51 million for rectal cancer, €234 million for breast cancer and €242 million for female genital cancers.Conclusions A considerable number of cancer cases can be attributed to SB, which also imposes a large health economic burden. Implementing effective prevention measures, such as workplace, school or commuting interventions, is needed to reduce the incidence of cancer attributable to this modifiable risk factor. |
| format | Article |
| id | doaj-art-1b0bfb232af74044ba16e419fb60712c |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMJ Publishing Group |
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| series | BMJ Open |
| spelling | doaj-art-1b0bfb232af74044ba16e419fb60712c2025-01-15T06:00:08ZengBMJ Publishing GroupBMJ Open2044-60552025-01-0115110.1136/bmjopen-2024-094304Burden of cancer attributable to sedentary behaviour in Germany: an epidemiological analysis of survey dataMichael Leitzmann0Wilm Quentin1Katharina Schaber2Tobias Pukrop3Michael J Stein4Carmen Jochem5Department of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, GermanyDepartment of Planetary & Public Health, University of Bayreuth, Bayreuth, GermanyDepartment of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, GermanyDepartment of Internal Medicine III, University Hospital Regensburg, Regensburg, GermanyDepartment of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, GermanyDepartment of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, GermanyObjectives Sedentary behaviour (SB) is associated with increased risks of breast, colorectal, endometrial, ovarian and rectal cancers. However, the number of cancer cases attributable to SB in Germany and the associated costs are unknown.Setting Numbers and proportions (population-attributable fractions, PAF) of new cancer cases attributable to SB with published risk estimates for Germany for the years 2024, 2030 and 2040.Participants Sex-specific and age-specific population projections, national cancer incidence and exposure data. Primary and secondary outcome measures: new cancer cases attributable to SB and healthcare costs associated with cancer cases attributable to SB in Germany for the year 2024.Results Estimated numbers of cancers attributable to SB are projected to be up to 7612 cases (6% of total cancer cases) in 2024, up to 7899 cases (6%) in 2030 and up to 8245 cases (6%) in 2040. The PAF attributable to SB in women is 3% for breast cancer, 8% for colon cancer, 9% for both endometrial and ovarian cancers and 2% for rectal cancer. In men, the PAF is 9% for colon cancer and 3% for rectal cancer. In 2024, the estimated costs of SB-attributable cancers are €270 million for colon cancer, €51 million for rectal cancer, €234 million for breast cancer and €242 million for female genital cancers.Conclusions A considerable number of cancer cases can be attributed to SB, which also imposes a large health economic burden. Implementing effective prevention measures, such as workplace, school or commuting interventions, is needed to reduce the incidence of cancer attributable to this modifiable risk factor.https://bmjopen.bmj.com/content/15/1/e094304.full |
| spellingShingle | Michael Leitzmann Wilm Quentin Katharina Schaber Tobias Pukrop Michael J Stein Carmen Jochem Burden of cancer attributable to sedentary behaviour in Germany: an epidemiological analysis of survey data BMJ Open |
| title | Burden of cancer attributable to sedentary behaviour in Germany: an epidemiological analysis of survey data |
| title_full | Burden of cancer attributable to sedentary behaviour in Germany: an epidemiological analysis of survey data |
| title_fullStr | Burden of cancer attributable to sedentary behaviour in Germany: an epidemiological analysis of survey data |
| title_full_unstemmed | Burden of cancer attributable to sedentary behaviour in Germany: an epidemiological analysis of survey data |
| title_short | Burden of cancer attributable to sedentary behaviour in Germany: an epidemiological analysis of survey data |
| title_sort | burden of cancer attributable to sedentary behaviour in germany an epidemiological analysis of survey data |
| url | https://bmjopen.bmj.com/content/15/1/e094304.full |
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