The carotenoid torularhodin alleviates NAFLD by promoting Akkermanisa muniniphila-mediated adenosylcobalamin metabolism

The carotenoid torularhodin alleviates NAFLD by promoting Akkermanisa muniniphila-mediated adenosylcobalamin metabolism

Abstract Torularhodin, a unique carotenoid, confers beneficial effects on nonalcoholic fatty liver disease (NAFLD). However, the precise mechanism underlying its therapeutic effects remains unknown. Here, we report that torularhodin alleviates NAFLD in male mice by modulating the gut microbiota. Add...

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Main Authors: Chang Liu, Xiaojiao Zheng, Jian Ji, Xuan Zhu, Xiaoning Liu, He Liu, Lichun Guo, Kun Ye, Shuang Zhang, Yong-jiang Xu, Xiulan Sun, Weibiao Zhou, Hoi Leong Xavier Wong, Yaoqi Tian, He Qian
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58500-3
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