Interplay of lung microbiome and epigenetics in former smokers: A machine learning and fuzzy logic approach on COPD progression

Interplay of lung microbiome and epigenetics in former smokers: A machine learning and fuzzy logic approach on COPD progression

The progression of Chronic Obstructive Pulmonary Disease (COPD) has been shown in many studies to be directly related to changes in epigenetic modification. This study aims to investigate the relationships between smoking status, lung microbiome dysbiosis, and the long-term effect of smoking persist...

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Bibliographic Details
Main Authors: Hamidreza Taherkhani, Azadeh Kavianfar, Hossein Lanjanian, Nazanin Hosseinkhan, Mahdieh Salimi, Sajjad Nematzadeh, Mohammad Mehdi Naghizadeh, Sadegh Azimzadeh, Ali Masoudi-Nejad
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Heliyon
Subjects:
Epigenetics
COPD
Machine learning
Lung microbiome
Metabolic models
Former smoker
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844025013258
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