Effectiveness of physician-based diagnosis versus diagnostic artificial intelligence algorithms in detecting communicable febrile diseases in Mexico

Background Digital medicine is an important tool in the current healthcare landscape. Fever is an important reason for evaluating patients at first and second levels of care and a frequent symptom of diseases subject to epidemiological surveillance. Objective To evaluate the diagnostic effectiveness...

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Main Authors: Enrique Alonso Medina Fuentes, Carmen Alicia Ruíz Valdez, Porfirio Felipe Hernández Bautista, David Alejandro Cabrera Gaytán, Guadalupe Minerva Olivas Fabela, José Alberto Mireles Garza, Olga María Alejo Martínez, Brenda Leticia Rocha Reyes, Alfonso Vallejos Parás, Lumumba Arriaga Nieto, Yadira Pérez Andrade, Leticia Jaimes Betancourt, Gabriel Valle Alvarado, Oscar Cruz Orozco, Mónica Grisel Rivera Mahey
Format: Article
Language:English
Published: SAGE Publishing 2025-06-01
Series:Digital Health
Online Access:https://doi.org/10.1177/20552076251353292
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Summary:Background Digital medicine is an important tool in the current healthcare landscape. Fever is an important reason for evaluating patients at first and second levels of care and a frequent symptom of diseases subject to epidemiological surveillance. Objective To evaluate the diagnostic effectiveness of various algorithms in detecting communicable diseases of epidemiological interest in febrile patients at Hospital General Regional No. 1, Cd. Obregón, Sonora. Methods An observational, descriptive, and retrospective study was conducted in a second-level hospital from 1 January 2022 to 31 December 2023, to determine Cohen's kappa and the sensitivity, specificity, positive and negative predictive values, precision and Youden's J index of diagnostic algorithms for 20 communicable diseases with respect to the doctors’ diagnoses. Results Diagnostic algorithms were applied to the data of 909 cases. The sensitivities of Mediktor®, an artificial neural network-based algorithm, a medical diagnostic algorithm and a composite diagnostic algorithm were 11.97%, 64.09%, 69.92% and 99.37%, respectively, and the corresponding specificities were 93.43%, 91.24%, 27.01% and 5.11%, respectively. The neural network-based method yielded the highest Youden's J index. Conclusions The medical diagnostic algorithm had the best sensitivity, whereas the specificity was greater for the two artificial intelligence algorithms.
ISSN:2055-2076