Esculetin inhibits the PI3K/Akt/mTOR pathway and enhances anti-colorectal cancer activity via binding to ENO1
IntroductionColorectal cancer (CRC) ranks as the third most prevalent malignant tumor worldwide and is the second leading cause of cancer-related mortality. At present, while its standard treatment consists of a combination of surgery and chemotherapy, metastasis and recurrence are generally associa...
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| Main Authors: | Jianing Ma, Miaomiao Zhang, Shulipan Mulati, Xinhua Nabi, Weiyi Zhang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1627114/full |
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