A study of HPV self-sampling by female residents in communities of Zhengzhou, Henan Province, China: a cross-sectional observational study
ObjectiveEvaluate the feasibility of HPV self-sampling typing and quantitative detection as a cervical cancer screening scheme, and provide new methods to reduce the incidence of cervical cancer.MethodsThis was a cross-sectional observational study of 1,228 female residents in communities in Zhengzh...
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Frontiers Media S.A.
2025-07-01
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| author | Zhe Yang Zhe Yang Zhe Yang Zhe Yang Yue Lu Yiping Zhang Yunfeng Zhang Jingyi Mu Jingyi Mu Jingyi Mu Yicheng Li Shihao Mei Shihao Mei Yuru Guo Yuru Guo Wanyue Zhang Wanyue Zhang Peiru Zhu Peiru Zhu Yongjie Li Yongjie Li Yongjie Li Yongjie Li Guiqin Chen Guiqin Chen Guiqin Chen Guiqin Chen Ruijiao Zhao Aixia Hu Rujia Fan Rujia Fan Rujia Fan Rujia Fan Yue Wang Yue Wang Yue Wang Yue Wang |
| author_facet | Zhe Yang Zhe Yang Zhe Yang Zhe Yang Yue Lu Yiping Zhang Yunfeng Zhang Jingyi Mu Jingyi Mu Jingyi Mu Yicheng Li Shihao Mei Shihao Mei Yuru Guo Yuru Guo Wanyue Zhang Wanyue Zhang Peiru Zhu Peiru Zhu Yongjie Li Yongjie Li Yongjie Li Yongjie Li Guiqin Chen Guiqin Chen Guiqin Chen Guiqin Chen Ruijiao Zhao Aixia Hu Rujia Fan Rujia Fan Rujia Fan Rujia Fan Yue Wang Yue Wang Yue Wang Yue Wang |
| author_sort | Zhe Yang |
| collection | DOAJ |
| description | ObjectiveEvaluate the feasibility of HPV self-sampling typing and quantitative detection as a cervical cancer screening scheme, and provide new methods to reduce the incidence of cervical cancer.MethodsThis was a cross-sectional observational study of 1,228 female residents in communities in Zhengzhou city, Henan Province, who participated in HPV self-sampling detection. All the samples were subjected to HPV typing and quantitative detection. HPV-positive individuals were recalled for further cervical liquid-based cytology and colposcopy.ResultsThe results of this study revealed that 33.71% of female residents lacked awareness of cervical cancer screening. Older age and low educational level are independent influencing factors for the lack of screening awareness. The overall positive rate of HPV was 18.89%. The three most common subtypes were types 16 (2.61%), 52 (2.44%), and 53 (2.28%). Results revealed that age at first sexual intercourse, sexual frequency, parity, having multiple sexual partners, cleaning behavior after sexual intercourse, and using condoms during sexual intercourse were factors related to HPV infection (P < 0.05). Logistic regression analysis revealed that age at first sexual intercourse ≤20 years, sexual frequency >2 times/week, parity >1 time, and having multiple sexual partners were risk factors for HPV infection (OR > 1, P < 0.05). Frequent cleaning after sexual intercourse and frequent use of condoms during sexual intercourse were protective factors against HPV infection (OR < 1, P < 0.05).ConclusionHPV self-sampling detection had a good experience and a high degree of acceptance, which can be promoted and applied in cervical cancer screening in Henan province. |
| format | Article |
| id | doaj-art-1afd6aed2f02468383892f859c908ff2 |
| institution | Kabale University |
| issn | 2296-2565 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
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| spelling | doaj-art-1afd6aed2f02468383892f859c908ff22025-08-20T03:30:01ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-07-011310.3389/fpubh.2025.15576781557678A study of HPV self-sampling by female residents in communities of Zhengzhou, Henan Province, China: a cross-sectional observational studyZhe Yang0Zhe Yang1Zhe Yang2Zhe Yang3Yue Lu4Yiping Zhang5Yunfeng Zhang6Jingyi Mu7Jingyi Mu8Jingyi Mu9Yicheng Li10Shihao Mei11Shihao Mei12Yuru Guo13Yuru Guo14Wanyue Zhang15Wanyue Zhang16Peiru Zhu17Peiru Zhu18Yongjie Li19Yongjie Li20Yongjie Li21Yongjie Li22Guiqin Chen23Guiqin Chen24Guiqin Chen25Guiqin Chen26Ruijiao Zhao27Aixia Hu28Rujia Fan29Rujia Fan30Rujia Fan31Rujia Fan32Yue Wang33Yue Wang34Yue Wang35Yue Wang36Department of Obstetrics and Gynecology, Henan Provincial People's Hospital, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, People's Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, People's Hospital of Henan University, Zhengzhou, ChinaHenan International Joint Laboratory of Early Diagnosis and Treatment of Gynecological Malignant Tumors, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, People's Hospital of Henan University, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, People's Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, People's Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, Henan Provincial People's Hospital, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, People's Hospital of Zhengzhou University, Zhengzhou, ChinaHenan International Joint Laboratory of Early Diagnosis and Treatment of Gynecological Malignant Tumors, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, People's Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, Henan Provincial People's Hospital, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, People's Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, Henan Provincial People's Hospital, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, People's Hospital of Henan University, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, Henan Provincial People's Hospital, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, People's Hospital of Henan University, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, Henan Provincial People's Hospital, Zhengzhou, ChinaHenan International Joint Laboratory of Early Diagnosis and Treatment of Gynecological Malignant Tumors, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, Henan Provincial People's Hospital, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, People's Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, People's Hospital of Henan University, Zhengzhou, ChinaHenan International Joint Laboratory of Early Diagnosis and Treatment of Gynecological Malignant Tumors, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, Henan Provincial People's Hospital, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, People's Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, People's Hospital of Henan University, Zhengzhou, ChinaHenan International Joint Laboratory of Early Diagnosis and Treatment of Gynecological Malignant Tumors, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, Henan Provincial People's Hospital, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, Henan Provincial People's Hospital, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, Henan Provincial People's Hospital, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, People's Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, People's Hospital of Henan University, Zhengzhou, ChinaHenan International Joint Laboratory of Early Diagnosis and Treatment of Gynecological Malignant Tumors, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, Henan Provincial People's Hospital, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, People's Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Obstetrics and Gynecology, People's Hospital of Henan University, Zhengzhou, ChinaHenan International Joint Laboratory of Early Diagnosis and Treatment of Gynecological Malignant Tumors, Zhengzhou, ChinaObjectiveEvaluate the feasibility of HPV self-sampling typing and quantitative detection as a cervical cancer screening scheme, and provide new methods to reduce the incidence of cervical cancer.MethodsThis was a cross-sectional observational study of 1,228 female residents in communities in Zhengzhou city, Henan Province, who participated in HPV self-sampling detection. All the samples were subjected to HPV typing and quantitative detection. HPV-positive individuals were recalled for further cervical liquid-based cytology and colposcopy.ResultsThe results of this study revealed that 33.71% of female residents lacked awareness of cervical cancer screening. Older age and low educational level are independent influencing factors for the lack of screening awareness. The overall positive rate of HPV was 18.89%. The three most common subtypes were types 16 (2.61%), 52 (2.44%), and 53 (2.28%). Results revealed that age at first sexual intercourse, sexual frequency, parity, having multiple sexual partners, cleaning behavior after sexual intercourse, and using condoms during sexual intercourse were factors related to HPV infection (P < 0.05). Logistic regression analysis revealed that age at first sexual intercourse ≤20 years, sexual frequency >2 times/week, parity >1 time, and having multiple sexual partners were risk factors for HPV infection (OR > 1, P < 0.05). Frequent cleaning after sexual intercourse and frequent use of condoms during sexual intercourse were protective factors against HPV infection (OR < 1, P < 0.05).ConclusionHPV self-sampling detection had a good experience and a high degree of acceptance, which can be promoted and applied in cervical cancer screening in Henan province.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1557678/fullcervical cancerHPV self-samplingcommunitiesearly screeningHPV typing and quantitative |
| spellingShingle | Zhe Yang Zhe Yang Zhe Yang Zhe Yang Yue Lu Yiping Zhang Yunfeng Zhang Jingyi Mu Jingyi Mu Jingyi Mu Yicheng Li Shihao Mei Shihao Mei Yuru Guo Yuru Guo Wanyue Zhang Wanyue Zhang Peiru Zhu Peiru Zhu Yongjie Li Yongjie Li Yongjie Li Yongjie Li Guiqin Chen Guiqin Chen Guiqin Chen Guiqin Chen Ruijiao Zhao Aixia Hu Rujia Fan Rujia Fan Rujia Fan Rujia Fan Yue Wang Yue Wang Yue Wang Yue Wang A study of HPV self-sampling by female residents in communities of Zhengzhou, Henan Province, China: a cross-sectional observational study Frontiers in Public Health cervical cancer HPV self-sampling communities early screening HPV typing and quantitative |
| title | A study of HPV self-sampling by female residents in communities of Zhengzhou, Henan Province, China: a cross-sectional observational study |
| title_full | A study of HPV self-sampling by female residents in communities of Zhengzhou, Henan Province, China: a cross-sectional observational study |
| title_fullStr | A study of HPV self-sampling by female residents in communities of Zhengzhou, Henan Province, China: a cross-sectional observational study |
| title_full_unstemmed | A study of HPV self-sampling by female residents in communities of Zhengzhou, Henan Province, China: a cross-sectional observational study |
| title_short | A study of HPV self-sampling by female residents in communities of Zhengzhou, Henan Province, China: a cross-sectional observational study |
| title_sort | study of hpv self sampling by female residents in communities of zhengzhou henan province china a cross sectional observational study |
| topic | cervical cancer HPV self-sampling communities early screening HPV typing and quantitative |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1557678/full |
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